C. L. Edwards, Sharena Scott, M. Boggan, J. Meek, W. J. Bryson, Alexandria McDougald, Milo Broadnax, C. Barker, Jessica Miller, J. Sollers, Tanisha I. Burford, J. Livingston, E. Whitworth, G. Byrd, Kelvin Williams, Sherry C. Eaton, Malik Muhammad, George Cliette, Dana Jones, Brianna Downey, Hilary T. Dietahin, Merrell Turner, Roland Thorpe, Keith Whitfield, Debra O. Parker, E. Robinson, M. Wood, Kenyon Railey, Shiv Sudhakar, Wandy Morel Cubilete, N. Shah
{"title":"A Rare Blood Malignancy in a Genetic Hematological Disorder: Polycythemia Vera (PV) in Sickle Cell Disease (SCD)","authors":"C. L. Edwards, Sharena Scott, M. Boggan, J. Meek, W. J. Bryson, Alexandria McDougald, Milo Broadnax, C. Barker, Jessica Miller, J. Sollers, Tanisha I. Burford, J. Livingston, E. Whitworth, G. Byrd, Kelvin Williams, Sherry C. Eaton, Malik Muhammad, George Cliette, Dana Jones, Brianna Downey, Hilary T. Dietahin, Merrell Turner, Roland Thorpe, Keith Whitfield, Debra O. Parker, E. Robinson, M. Wood, Kenyon Railey, Shiv Sudhakar, Wandy Morel Cubilete, N. Shah","doi":"10.33696/haematology.4.053","DOIUrl":null,"url":null,"abstract":"Objective: To delineate the etiology, symptomatology, and treatment of Polycythemia Vera in adults with Sickle Cell Disease. The current review contains a review of the 4 case reports that we found on the topic. To our knowledge, no other case reports exist. \nMethods: We reviewed the scientific literature to discover case reports that included the topic of PV. We noted consistencies in presentation, evaluation, treatment, and clinical outcomes.\nResults: We reviewed 4 case reports and a limited number of clinical papers on PV in SCD. We found and reported on consistencies in clinical presentation and the diversity of treatments. We reported hematological, bone marrow, and radiographic findings.\nConclusions: There is great variability in the evaluation and treatment of cases of PV in SCD. We advocate for more research and deconstructing the complicated relationship between these two comorbid disorders.","PeriodicalId":87297,"journal":{"name":"Journal of clinical haematology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical haematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33696/haematology.4.053","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To delineate the etiology, symptomatology, and treatment of Polycythemia Vera in adults with Sickle Cell Disease. The current review contains a review of the 4 case reports that we found on the topic. To our knowledge, no other case reports exist.
Methods: We reviewed the scientific literature to discover case reports that included the topic of PV. We noted consistencies in presentation, evaluation, treatment, and clinical outcomes.
Results: We reviewed 4 case reports and a limited number of clinical papers on PV in SCD. We found and reported on consistencies in clinical presentation and the diversity of treatments. We reported hematological, bone marrow, and radiographic findings.
Conclusions: There is great variability in the evaluation and treatment of cases of PV in SCD. We advocate for more research and deconstructing the complicated relationship between these two comorbid disorders.