Chemical properties and protective effect of Rosmarinus officinalis: Mitigation of lipid peroxidation and DNA-damage from arsenic exposure

IF 1.2 4区生物学 Q2 Agricultural and Biological Sciences

Journal of Applied Botany and Food Quality-Angewandte Botanik Pub Date : 2018-02-28 DOI:10.5073/JABFQ.2018.091.001

J. Farias, V. Frescura, A. Boligon, Kássia Cauana Trapp, J. L. Andriolo, S. Tedesco, K. Bernardy, R. Schwalbert, B. D. Frari, M. Carey, F. Nicoloso

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引用次数: 3

Abstract

Recent studies have implicated dietary factors in the cause and prevention of important diseases, with strong evidence that plant’s compounds can protect against these diseases. Moreover, food security and environmental contamination are topics in focus at the moment. In this view, contamination by arsenic (As) has received much attention as well as some spices with medicinal properties. Among these plants, the use of Rosmarinus officinalis L. has demonstrated antioxidant properties besides being used for circulatory disorders. Therefore, we measured the mitotic index of Allium cepa L. and characterized the antioxidant effects to determine the capacity of R. officinalis to ameliorate arsenic-induced DNA damage. R. officinalis extract showed no mutagenic effects and exhibited antimutagenic potential, reducing the DNA damage, anaphase-telophase briges and micronuclei chromosome aberrations that result from treatment with the arsenic. Additionally, reduction in arsenic- induced lipid peroxidation was also observed.

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迷迭香的化学性质和保护作用:减轻砷暴露引起的脂质过氧化和dna损伤

最近的研究表明，饮食因素与重要疾病的病因和预防有关，有力的证据表明，植物的化合物可以预防这些疾病。此外，粮食安全和环境污染是目前关注的焦点。在这种观点中，砷（As）的污染以及一些具有药用性质的香料受到了广泛关注。在这些植物中，除了用于循环系统疾病外，迷迭香的使用还显示出抗氧化特性。因此，我们测量了洋葱的有丝分裂指数，并对其抗氧化作用进行了表征，以确定R.officinalis改善砷诱导的DNA损伤的能力。巴戟天提取物并没有显示出诱变作用，并显示出抗突变的潜力，减少了砷处理引起的DNA损伤、后期末期明亮和微核染色体畸变。此外，还观察到砷诱导的脂质过氧化减少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Applied Botany and Food Quality-Angewandte Botanik 生物-植物科学

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The Journal of Applied Botany and Food Quality is the Open Access journal of the German Society for Quality Research on Plant Foods and the Section Applied Botany of the German Botanical Society. It provides a platform for scientists to disseminate recent results of applied plant research in plant physiology and plant ecology, plant biotechnology, plant breeding and cultivation, phytomedicine, plant nutrition, plant stress and resistance, plant microbiology, plant analysis (including -omics techniques), and plant food chemistry. The articles have a clear focus on botanical and plant quality aspects and contain new and innovative information based on state-of-the-art methodologies.