The Effect in the Acid-Base Status, Electrolyte Levels and Anion-Gap Following Fluid Resuscitation with Normal Saline, Lactated Ringers and Isotonic Electrolyte Solution Fluids Among Pediatric Patients

Abstract

Background: Currently, the increasing number of available fluids has generated controversy about the optimal choice of resuscitation fluid. Popular intravenous fluids in clinical use may have an impact on electrolyte concentration and metabolic balance and each resuscitation fluid should be considered as a powerful pharmacological agent. Based on the non-physiological composition of normal saline, the interest to find a fluid that will provide the optimal composition has moved from synthetic colloid solutions to more physiologic balanced solutions.