Brief Introduction of Important Innate Cells in Roles of Asthma

Abstract

Asthma is a chronic inflammatory disease with multifactorial disorder of the airways, and was associated with T helper type 2 (TH2) cells. It is considered the results of complicated interactions between innate cells and structural cells, including dendritic cells (DCs), epithelial cells, mast cells (MCs), basophils, eosinophils and group 2 innate lymphoid cells (ILC2s), which finally sustains Th2 immunity in the pathogenesis of asthma. In this narrative review the details of roles of important innate cells against asthma are discussed to facilitate the future study of asthma.