Socio-demographic and clinico-pathologic pattern of patients with colorectal cancers seen in Ahmadu Bello University Teaching Hospital, Zaria

IF 0.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
H. Theyra-Enias, S. Adewuyi, A. Alabi, Desiree Jummai, I. Zubairu
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Abstract

Introduction: Colorectal cancer is a major cause of morbidity and mortality in the world. It accounts for 10.2% of cancer incidence globally, with a mortality of 9.2%. It ranks third in terms of incidence but second in terms of mortality. Colorectal cancer is not uniformly common throughout the world. Its incidence is increasing in developing countries, probably due to the acquisition of western lifestyle. Aim: The aim of this study was to determine the sociodemographic and clinicopathological pattern of patients with colorectal cancer seen in the Department of Surgery, Radiotherapy, and Oncology Centre, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, over a 10-year period. Materials and Methods: In this retrospective study, data were collected from the case files and treatment cards of 122 patients with colorectal cancer managed at the Surgical, Radiotherapy, and Oncology Department of ABUTH, Zaria, from January 2006 to December 2015. Data items analyzed included age, sex, residential area, occupation, duration of symptoms, presenting complaints, subsite, histological type, grade, and stage. All analyses were performed by SPSS version 20. Results: An annual incidence of 12.2 cases/annum was seen. Seventy (57.4%) were male and 52 (42.6%) were female. Male:female ratio was 1.3:1 and the age range was between 12 years and 78 years, majority were between 31 and 40 years (24.6%), with a mean age of 42.4 years and median age of 41 years. It was found to be more common among the urban dwellers, with the public/civil servants being the most affected (36.0%). The duration of presenting complain ranged from 3 weeks to 10 years, most patients presenting at 7–10 months with more than one symptom. Bleeding per rectum was the most common symptom seen in 20%. Adenocarcinoma was the predominant histology seen in 73% (n = 89) and 28.7% were well differentiated. The rectum was the most common subsite, while left-sided lesions (20%) were more common than right-sided lesions (17%). About 18% (n = 22) had distant metastasis. Conclusion: The study showed that colorectal cancer was more common among the younger age group, with a slight male preponderance. They were mostly urban dwellers and civil/public servants. The most common presenting symptom was bleeding per rectum and majority of the cases presented at an advanced stage. Early detection through public health education, screening programs, affordable and effective treatment, and follow-up will help reverse this trend. Conclusion: The study showed that colorectal cancer was more common among the younger age group, with a slight male preponderance. They were mostly urban dwellers and civil/public servants. Bleeding per rectum being the most common complaint, majority of the cases presented at an advanced stage. Early detection through public health education, screening programs, affordable and effective treatment, and follow-up will help reverse this trend.
扎里亚Ahmadu Bello大学教学医院结直肠癌患者的社会人口统计学和临床病理模式
导读:结直肠癌是世界上发病率和死亡率的主要原因。它占全球癌症发病率的10.2%,死亡率为9.2%。发病率排名第三,死亡率排名第二。结直肠癌在全世界并不普遍。其发病率在发展中国家正在增加,可能是由于西方生活方式的习得。目的:本研究的目的是确定扎里亚Ahmadu Bello大学教学医院(ABUTH)外科、放疗和肿瘤中心10年来结直肠癌患者的社会人口学和临床病理模式。材料与方法:本回顾性研究收集了2006年1月至2015年12月在扎里亚州ABUTH外科、放疗和肿瘤科治疗的122例结直肠癌患者的病例档案和治疗卡片。分析的数据项目包括年龄、性别、居住地、职业、症状持续时间、主诉、亚部位、组织学类型、分级和分期。所有分析均采用SPSS version 20进行。结果:年发病率12.2例/年。男性70例(57.4%),女性52例(42.6%)。男女比例为1.3:1,年龄范围在12 ~ 78岁之间,以31 ~ 40岁居多(24.6%),平均年龄42.4岁,中位年龄41岁。在城市居民中更为常见,其中公共/公务员受影响最大(36.0%)。主诉持续时间从3周到10年不等,大多数患者在7-10个月时出现不止一种症状。直肠出血是最常见的症状,占20%。腺癌是主要的组织学,73% (n = 89), 28.7%为高分化。直肠是最常见的亚部位,而左侧病变(20%)比右侧病变(17%)更常见。约18% (n = 22)有远处转移。结论:研究表明,结直肠癌在年轻人群中更为常见,男性略占优势。他们大多是城市居民和公务员。最常见的症状是直肠出血,大多数病例出现在晚期。通过公共卫生教育、筛查项目、负担得起的有效治疗以及后续行动进行早期发现,将有助于扭转这一趋势。结论:研究表明,结直肠癌在年轻人群中更为常见,男性略占优势。他们大多是城市居民和公务员。直肠出血是最常见的主诉,大多数病例出现在晚期。通过公共卫生教育、筛查项目、负担得起的有效治疗以及后续行动进行早期发现,将有助于扭转这一趋势。
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West African Journal of Radiology
West African Journal of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
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