Characteristics of 185 thyroid micropapillary carcinoma patients undergoing 131I treatment

中华核医学与分子影像杂志 Pub Date : 2019-09-25 DOI:10.3760/CMA.J.ISSN.2095-2848.2019.09.005

Y. Long, Cai-xia An

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引用次数: 1

Abstract

Objective To compare the clinical features of papillary thyroid microcarcinoma (PTMC) and non-microcarcinoma papillary thyroid carcinoma (PTC). Methods Clinical data of 522 patients (156 males, 366 females, age: 16-77 years) with PTC treated with 131I from January 2014 to September 2018 were analyzed retrospectively. Patients were divided into PTMC group (46 males, 139 females, age: (38.5±6.5) years; tumor diameter≤1.0 cm) and non-microcarcinoma PTC group (110 males, 227 females, age: (40.5±4.5) years; tumor diameter>1.0 cm). General information and TNM status of patients were compared. The t′ test and χ2 test were used to analyze the data. Results Patients was relatively young in PTMC group (t′=2.20, P 0.05; mostly females). The incidence of extraglandular invasion in PTMC group was significantly lower than that in PTC group (33.51%(62/185) vs 56.08%(189/337); χ2=24.37, P 0.05). Conclusions Clinical characteristics of PTC can be influenced by tumor diameter. The features of primary tumor and lymph node metastasis between patients with moderate- and high-risk PTMC and non-microcarcinoma PTC patients are similar, which suggests that 131I therapy is necessary to patients with moderate- and high-risk PTMC. Key words: Thyroid neoplasms; Carcinoma, papillary; Radiotherapy; Iodine radioisotopes

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185例甲状腺微乳头状癌131I治疗特点分析

目的比较甲状腺乳头状微癌(PTMC)与非微癌甲状腺乳头状癌(PTC)的临床特点。方法回顾性分析2014年1月~ 2018年9月522例PTC患者(男156例，女366例，年龄16 ~ 77岁)的临床资料。患者分为PTMC组(男性46例，女性139例)，年龄(38.5±6.5)岁;肿瘤直径≤1.0 cm)和非微癌PTC组(男性110例，女性227例，年龄(40.5±4.5)岁;肿瘤直径>1.0 cm)。比较患者的一般情况和TNM状态。采用t检验和χ2检验对数据进行分析。结果PTMC组患者年龄相对较轻(t ' =2.20, p0.05;主要是女性)。PTMC组腺外侵犯发生率明显低于PTC组(33.51%(62/185)vs 56.08%(189/337);χ2=24.37, p 0.05)。结论PTC的临床特征受肿瘤直径的影响。中、高危PTMC患者与非微癌PTC患者原发肿瘤及淋巴结转移特征相似，提示中、高危PTMC患者需要131I治疗。关键词:甲状腺肿瘤;癌,乳头状;放射治疗;碘的放射性同位素

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来源期刊

中华核医学与分子影像杂志核医学，分子影像

自引率

0.00%

发文量

5088

期刊介绍： Chinese Journal of Nuclear Medicine and Molecular Imaging (CJNMMI) was established in 1981, with the name of Chinese Journal of Nuclear Medicine, and renamed in 2012. As the specialized periodical in the domain of nuclear medicine in China, the aim of Chinese Journal of Nuclear Medicine and Molecular Imaging is to develop nuclear medicine sciences, push forward nuclear medicine education and basic construction, foster qualified personnel training and academic exchanges, and popularize related knowledge and raising public awareness. Topics of interest for Chinese Journal of Nuclear Medicine and Molecular Imaging include: -Research and commentary on nuclear medicine and molecular imaging with significant implications for disease diagnosis and treatment -Investigative studies of heart, brain imaging and tumor positioning -Perspectives and reviews on research topics that discuss the implications of findings from the basic science and clinical practice of nuclear medicine and molecular imaging - Nuclear medicine education and personnel training - Topics of interest for nuclear medicine and molecular imaging include subject coverage diseases such as cardiovascular diseases, cancer, Alzheimer’s disease, and Parkinson’s disease, and also radionuclide therapy, radiomics, molecular probes and related translational research.