Porphyromonas gingivalis bacterium as a risk factor for Alzheimer’s disease!

Abstract

Alzheimer’s disease remains a significant socio-economic problem in modern medicine. This disease is a neurodegenerative one that is characterized by the plaque formation and neurofibrillary tangles, due to the accumulation of β-amyloid peptide in the medial regions of the temporal lobe and the neocortical regions of the brain. It is impossible to name the sole cause of Alzheimer's disease; however, the features of pathogenesis of this disease are known, including cholinergic deficiency; beta-amyloid