Analysis of unsteady non-Newtonian Jeffrey blood flow and transport of magnetic nanoparticles through an inclined porous artery with stenosis using the time fractional derivative

IF 2.7 3区 物理与天体物理 Q2 PHYSICS, APPLIED
Habtamu Bayissa Yadeta, S. Shaw
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Abstract

In the present study, a Caputo–Fabrizio (C–F) time-fractional derivative is introduced to the governing equations to present the flow of blood and the transport of magnetic nanoparticles (MNPs) through an inclined porous artery with mild stenosis. The rheology of blood is defined by the non-Newtonian visco-elastic Jeffrey fluid. The transport of MNPs is used as a drug delivery application for cardiovascular disorder therapy. The momentum and transport equations are solved analytically by using the Laplace transform and the finite Hankel transform along with their inverses, and the solutions are presented in the form of Laplace convolutions. To display the solutions graphically, the Laplace convolutions are solved using the numerical integration technique. The study presents the impacts of different governing parameters on blood and MNP velocities, volumetric flow rate, flow resistance, and skin friction. The study demonstrates that blood and MNP velocities boost with an increase in the fractional order parameter, Darcy number, and Jeffrey fluid parameter. The volumetric flow rate decreases and flow resistance increases with enhancement in stenosis height. The non-symmetric shape of stenosis and the rheology of blood decrease skin friction, whereas enhancement in MNP concentration increases skin friction. A comparison of the present result with the previous work shows excellent agreement. The present study will be beneficial for the field of medical science to further study atherosclerosis therapy and other similar disorders.
利用时间分数导数分析非稳态非牛顿杰弗里血流和磁性纳米颗粒通过狭窄倾斜多孔动脉的运输
在本研究中,在控制方程中引入了Caputo-Fabrizio (C-F)时间分数导数,以表示血液流动和磁性纳米颗粒(MNPs)通过轻度狭窄的倾斜多孔动脉的运输。血液的流变学是由非牛顿粘弹性杰弗里流体定义的。MNPs的转运被用作心血管疾病治疗的药物递送应用。利用拉普拉斯变换和有限汉克尔变换及其逆对动量方程和输运方程进行了解析求解,并以拉普拉斯卷积的形式给出了解。为了图形化地显示解,使用数值积分技术求解拉普拉斯卷积。该研究展示了不同控制参数对血液和MNP速度、体积流速、流动阻力和皮肤摩擦的影响。研究表明,血液和MNP速度随着分数阶参数、达西数和杰弗里流体参数的增加而增加。随着狭窄高度的增加,体积流量减小,流动阻力增大。狭窄的非对称形状和血液的流变性降低了皮肤摩擦,而MNP浓度的增加则增加了皮肤摩擦。将目前的结果与以前的工作进行比较,结果非常吻合。本研究将有助于医学领域进一步研究动脉粥样硬化和其他类似疾病的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Applied Physics
Journal of Applied Physics 物理-物理:应用
CiteScore
5.40
自引率
9.40%
发文量
1534
审稿时长
2.3 months
期刊介绍: The Journal of Applied Physics (JAP) is an influential international journal publishing significant new experimental and theoretical results of applied physics research. Topics covered in JAP are diverse and reflect the most current applied physics research, including: Dielectrics, ferroelectrics, and multiferroics- Electrical discharges, plasmas, and plasma-surface interactions- Emerging, interdisciplinary, and other fields of applied physics- Magnetism, spintronics, and superconductivity- Organic-Inorganic systems, including organic electronics- Photonics, plasmonics, photovoltaics, lasers, optical materials, and phenomena- Physics of devices and sensors- Physics of materials, including electrical, thermal, mechanical and other properties- Physics of matter under extreme conditions- Physics of nanoscale and low-dimensional systems, including atomic and quantum phenomena- Physics of semiconductors- Soft matter, fluids, and biophysics- Thin films, interfaces, and surfaces
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