Investigation and Analysis of the Current Situation of VAE Preventive Measures in ICU in Beijing-Tianjin-Hebei Urban Agglomeration of China

Abstract

of developing pneumonia. Benzodiazepines and propofol were associated with an increased VAE risk, but not dexmedetomidine [12]. 3) Low tidal volume ventilation (LTVV): Several studies have shown that low tidal volume MV reduce ARDS, atelectasis, and lung infections in patients without ARDS [13-15]. 4) Maintenance of gastric acid: Anti-ulcerative agents are prophylactically administered in MV patients to prevent stress ulcers. The increased pH of gastric juice caused by anti-ulcerative agents has been shown to promote proliferation of pathogenic bacteria in the stomach. Aspiration of these bacteria is considered as one of the causes of VAP. Studies have shown that administration of anti-ulcerative agents that did not affect gastric acidity, such as sucralfate had a lower incidence of VAP, compared to proton pump inhibitors and H2 receptor blockers [16].