A study on the thermal responsive behavior of hydrogel-based materials and their potential use in medical applications

IF 1.6 4区工程技术 Q3 INSTRUMENTS & INSTRUMENTATION

Sensor Review Pub Date : 2022-10-11 DOI:10.1108/sr-10-2021-0366

Aniqa Junaid, Murtaza Najabat Ali, Mariam Mir, Sadia Hassan

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引用次数: 2

Abstract

Purpose The purpose of this paper is to present synthesis protocol of hydrogel composed of Chitosan (CS) and Poly(ethylene glycol) (PEG) and establish an understanding of its thermal responsive behavior. It aims to prove the basic temperature sensing ability of a novel CS-PEG-based hydrogel and define its sensing span. Design/methodology/approach This study includes synthesis of CS and PEG-based hydrogel samples by first performing dissolution of both constituents, respectively, and then adding Glutaraldehyde as the cross-linking agent. It further includes proposed hydrogel’s swelling studies and dynamic behavior testing, followed by hydrogel characterization by Fourier transform infrared spectroscopy, X-ray diffraction and SEM. The last section focuses on the use of proposed hydrogel as a temperature sensor. Findings Detailed experimental results show that a hydrogel comprising of CS and PEG presents a thermally responsive behavior. It offers potential to be used as a temperature responsive hydrogel-based sensor which could be used in medical applications. Originality/value This research study presents scope for future research in the field of thermally responsive bio-sensors. It provides basis for the fabrication of a thermal responsive sensor system based on hydrogels that can be used in specific medical applications.

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水凝胶基材料的热响应行为及其在医学应用中的潜在应用研究

目的介绍由壳聚糖（CS）和聚乙二醇（PEG）组成的水凝胶的合成方案，并对其热响应行为进行了解。旨在证明新型CS-PEG水凝胶的基本温度传感能力，并确定其传感范围。设计/方法/方法本研究包括通过首先分别溶解CS和PEG两种成分，然后加入戊二醛作为交联剂来合成基于CS和PEG的水凝胶样品。它进一步包括所提出的水凝胶的溶胀研究和动态行为测试，然后通过傅立叶变换红外光谱、X射线衍射和SEM对水凝胶进行表征。最后一节重点介绍了所提出的凝胶作为温度传感器的用途。详细的实验结果表明，由CS和PEG组成的水凝胶表现出热响应行为。它具有用作基于水凝胶的温度响应传感器的潜力，可用于医疗应用。原创性/价值这项研究为热响应生物传感器领域的未来研究提供了空间。它为制造可用于特定医疗应用的基于水凝胶的热响应传感器系统提供了基础。

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来源期刊

Sensor Review 工程技术-仪器仪表

CiteScore

3.40

自引率

6.20%

发文量

审稿时长

3.7 months

期刊介绍： Sensor Review publishes peer reviewed state-of-the-art articles and specially commissioned technology reviews. Each issue of this multidisciplinary journal includes high quality original content covering all aspects of sensors and their applications, and reflecting the most interesting and strategically important research and development activities from around the world. Because of this, readers can stay at the very forefront of high technology sensor developments. Emphasis is placed on detailed independent regular and review articles identifying the full range of sensors currently available for specific applications, as well as highlighting those areas of technology showing great potential for the future. The journal encourages authors to consider the practical and social implications of their articles. All articles undergo a rigorous double-blind peer review process which involves an initial assessment of suitability of an article for the journal followed by sending it to, at least two reviewers in the field if deemed suitable. Sensor Review’s coverage includes, but is not restricted to: Mechanical sensors – position, displacement, proximity, velocity, acceleration, vibration, force, torque, pressure, and flow sensors Electric and magnetic sensors – resistance, inductive, capacitive, piezoelectric, eddy-current, electromagnetic, photoelectric, and thermoelectric sensors Temperature sensors, infrared sensors, humidity sensors Optical, electro-optical and fibre-optic sensors and systems, photonic sensors Biosensors, wearable and implantable sensors and systems, immunosensors Gas and chemical sensors and systems, polymer sensors Acoustic and ultrasonic sensors Haptic sensors and devices Smart and intelligent sensors and systems Nanosensors, NEMS, MEMS, and BioMEMS Quantum sensors Sensor systems: sensor data fusion, signals, processing and interfacing, signal conditioning.