Scientific Session IV: Thoracic

Abstract

Objective: Composite trachea grafts made of collagen supported by 3D-printed plastic scaffolds contain void spaces between construct layers. To enhance cellular infiltration and support graft integrity, we developed a composite collagen-agarose hydrogel that permeates the entire graft providing a continuous cell substrate from the external side of the graft through to the lumen. In this study, we assessed the capacity of this hydrogel to support in vitro angiogenesis. Methods: Human C11-1). Conclusions: This study demonstrates decreased waitlist time with increased incidence of CHK transplantation in the new policy era. Despite the improved CHK transplant-ability in the new allocation system, survival on the waitlist and post-transplant outcomes are comparable to the previous 3-tier system.