Barriers to Medications Adherence among Uncontrolled Type 2 Diabetic Patients in PHCs, Riyadh, Saudi Arabia

Hosam Khalid Alsahabi, O. Almousa, B. Khalid, Alsahabi, Nourah Aljasser
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Abstract

Introduction: Diabetes Mellitus is one of the most common metabolic problems in Saudi Arabia and its chronic progressive disease is characterized by numerous health complications. Diabetes is a growing medical problem and the costs to society are great and rising. The recent report formed by International Diabetes Federation Diabetes Atlas values that there are presently 387 million people alive with diabetes globally in 2014, a 105% rise from its last report in 2011 with the highest number of people living in the western pacific. A recent systematic analysis study on global load disease analyzed data from health examination surveys and epidemiological studies involving data from 2.7 million participants and 370 country-years reports that a total of 347 million adults are alive with diabetes worldwide. Aim: This study aimed to improve health services provided to Diabetic patients and identify the barriers to medication adherence in those who attend Wazarat health center, chronic illness clinics. Methods: A descriptive, observation retrospective case-control study enrolled 162 patients with type 2 diabetes aged 35 years and above at Prince Sultan Military Medical City (PSMMC), Wazarat Health Center, Riyadh, KSA within two years (Year 2020-2021). Using a probability stratified sampling method, we recruited patients who were able to provide a consent form, following up in chronic illness clinics and received treatment for at least 3 months and actively filled prescriptions for medications related to a chronic disease were subjects of this study. The sample was collected from chronic illness clinics, in which where the majority of patients were uncontrolled type 2 diabetes due to the COVID-19 pandemic. The target HbA1C is 7%. Results: The prevalence of poor glycemic control was 67.9% and the prevalence of poor glycemic control was significantly higher among females (p=0.031), those who have blood glucose devices at home (p=0.032), those who regularly monitored blood glucose levels (p=0.001) and those with a regular visit to DM clinic (p=0.001). The most common barrier to medication was fear of side effects (20.4%) and taking too many drugs (19.1%). Non-adherence to medication was significantly more common among those with uncontrolled HbA1c (p=0.022), those who did not receive education about medication side effects (p=0.010), and those who were non-adherence to diet and exercise (p=0.001). Conclusion: More than one-third of the diabetic population was non-adherence to diabetic medication. Patients with poor glycemic control who did not receive education about medication side effects and who were non-compliance with diet and exercise were more likely to be non-adherent to Diabetes mellitus medication.
沙特阿拉伯利雅得PHC中未控制的2型糖尿病患者药物依从性障碍
糖尿病是沙特阿拉伯最常见的代谢问题之一,其慢性进行性疾病的特点是许多健康并发症。糖尿病是一个日益严重的医疗问题,给社会带来的成本巨大且不断上升。国际糖尿病联合会糖尿病地图集最近编制的报告指出,2014年全球目前有3.87亿糖尿病患者,比2011年的上一份报告增加了105%,其中西太平洋地区的糖尿病患者人数最多。最近一项关于全球负荷疾病的系统分析研究分析了来自健康检查调查和流行病学研究的数据,涉及270万参与者和370个国家/年报告的数据,这些报告表明全世界共有3.47亿成年人患有糖尿病。目的:本研究旨在改善为糖尿病患者提供的医疗服务,并确定在Wazarat健康中心,慢性病诊所就诊的糖尿病患者的药物依从性障碍。方法:一项描述性、观察性、回顾性病例对照研究,纳入了沙特利雅得苏丹王子军事医疗城(PSMMC) Wazarat卫生中心两年内(2020-2021年)162例35岁及以上的2型糖尿病患者。采用概率分层抽样方法,我们招募了能够提供同意书,在慢性病诊所随访,接受治疗至少3个月,并积极填写慢性病相关药物处方的患者作为本研究的对象。样本是从慢性病诊所收集的,其中大多数患者由于COVID-19大流行而患有未控制的2型糖尿病。目标糖化血红蛋白为7%。结果:血糖控制不良的患病率为67.9%,其中女性(p=0.031)、家中有血糖仪(p=0.032)、定期监测血糖(p=0.001)和定期就诊糖尿病门诊(p=0.001)血糖控制不良的患病率显著高于女性(p=0.031)。最常见的用药障碍是害怕副作用(20.4%)和服药过多(19.1%)。在HbA1c未控制的患者(p=0.022)、未接受药物副作用教育的患者(p=0.010)以及未坚持饮食和运动的患者(p=0.001)中,不遵守药物治疗的情况更为常见。结论:超过三分之一的糖尿病患者不遵守糖尿病药物治疗。血糖控制较差的患者没有接受药物副作用的教育,不遵守饮食和运动的患者更有可能不坚持糖尿病药物治疗。
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