The image characteristics of optical coherence tomography in patients of acquired immunodeficiency syndrome with cytomegalovirus retinitis

Q4 Medicine

中华眼底病杂志 Pub Date : 2020-01-25 DOI:10.3760/CMA.J.ISSN.1005-1015.2020.01.002

Shengnan Wang, Huiyu Sun, Fei-fei Mao, Dan Li

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Abstract

Objective To observe the image characteristics of OCT in patients of acquired immunodeficiency syndrome (AIDS) with cytomegalovirus retinitis (CMVR). Methods Thirty-nine eyes of 26 patients of AIDS with CMVR diagnosed in Department of ophthalmology of Beijing Ditan Hospital Capital Medical University from January 2015 to December 2017 were included in this study. All the patients were males, with the mean age of 33.12±9.87 years. All the patients underwent the OCT examination by Spectralis HRA+OCT. The locations of scanning were macular, optical papilla and posterior pole of retina with retinitis. Typical images were saved and analyzed. Results The OCT pathological changes of CMVR included increase of retinal thickness and reflex of retina, indiscernible retinal layers, irregularity or absent external limiting membrane and/or ellipsoid zone, hyperreflective spots, vitreous cells. Among 39 eyes, there were 6 eyes with strong point-like reflection in the outer layer of retina around the lesion, 31 eyes (79.49%) with strong point-like reflection in the full layer of retina, 25 eyes (64.10%) with lesion involved macular area, 34 eyes (87.17%) with vitreous cells. Conclusions OCT images of the eyes with AIDS with CMVR were characterized by lesions involving the whole retina. Absent ellipsoid zone or structural changes can be seen in the affected areas and peripheral areas of the lesion. Key words: Acquired immunodeficiency syndrome/complications; Cytomegalovirus retinitis/diagnosis; Tomography, optical coherence

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获得性免疫缺陷综合征合并巨细胞病毒视网膜炎患者的光学相干断层扫描图像特征

目的观察获得性免疫缺陷综合征（AIDS）合并巨细胞病毒性视网膜炎（CMVR）患者OCT的图像特征。方法选择首都医科大学附属北京地坛医院眼科2015年1月至2017年12月诊断为CMVR型艾滋病患者26例，共39眼。患者均为男性，平均年龄33.12±9.87岁。所有患者均采用Spectralis HRA+OCT进行OCT检查。扫描部位为黄斑、视乳头和视网膜后极伴视网膜炎。保存并分析了典型图像。结果CMVR的OCT病理变化包括视网膜厚度和反射增加、视网膜层不清、外界膜和/或椭球区不规则或缺失、高反射点、玻璃体细胞。39眼中，病变周围视网膜外层强点状反射6眼，视网膜全层强点状反射31眼（79.49%），病变累及黄斑区25眼（64.10%），玻璃体细胞34眼（87.17%）。结论艾滋病合并CMVR患者的OCT图像以累及整个视网膜的病变为特征。在病变的受累区域和外围区域可以看到不存在椭球区或结构变化。关键词：获得性免疫缺陷综合征/并发症；巨细胞病毒性视网膜炎/诊断；层析成像，光学相干

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来源期刊

中华眼底病杂志 Medicine-Ophthalmology

CiteScore

0.40

自引率

0.00%

发文量

5383

期刊介绍： Chinese Journal of Ocular Fundus Diseases is the only scientific journal in my country that focuses on reporting fundus diseases. Its purpose is to combine clinical and basic research, and to give equal importance to improvement and popularization. It comprehensively reflects the leading clinical and basic research results of fundus disease disciplines in my country; cultivates professional talents in fundus disease, promotes the development of fundus disease disciplines in my country; and promotes academic exchanges on fundus disease at home and abroad. The coverage includes clinical and basic research results of posterior segment diseases such as retina, uveal tract, vitreous body, visual pathway, and internal eye diseases related to systemic diseases. The readers are medical workers and researchers related to clinical and basic research of fundus diseases. According to the journal retrieval report of the Chinese Institute of Scientific and Technological Information, the comprehensive ranking impact factor and total citation frequency of the Chinese Journal of Ocular Fundus Diseases have been among the best in the disciplines of ophthalmology, otolaryngology, and ophthalmology in my country for many years. The papers published have been included in many important databases at home and abroad, such as Scopus, Peking University Core, and China Science Citation Database (CSCD).