Systematic review of enhanced recovery after surgery in perioperative management of pancreaticoduodenectomy: a meta-analysis of randomized controlled trials and non-randomized controlled trials
Tao Zhang, Liang Yu, Shunli Fan, Fei Pan, Dong Zhang, Q. He
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引用次数: 1
Abstract
Objective
To systematically review the safety and efficacy of enhanced recovery after surgery (ERAS) in perioperative management of pancreaticoduodenectomy.
Methods
A search was performed in databases (including PubMed, EMASE, Cochrane library, Sinomed, Wangfang, VIP, and CNKI) for randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) up to September 2016 on use of ERAS in patients undergoing pancreaticoduodenectomy. After quality evaluation and data extraction, meta-analysis was performed using RevMan 5.3.
Results
Four RCTs and Twelve NRCTs involving a total of 2 828 patients were included. 1 401 patients were in the ERAS group, and 1 427 in the control group. Meta-analysis results showed that compared with the control group, the ERAS group had shorter length of hospital stay (SMD=-0.36, 95% CI=-0.44--0.28, P 0.05).
Conclusion
It is reasonably safe and efficacious to adopt ERAS in periopetative management of patients undergoing pancreaticoduodenectomy.
Key words:
Enhanced recovery after surgery; Pancreaticoduodenectomy; Perioperative; Meta-analysis