Distinct imaging features of different pathological subtypes of B cell non-Hodgkin′s lymphomas of the nose and pharynx ministry type NK/T cell

中国临床实用医学 Pub Date : 2017-10-25 DOI:10.3760/CMA.J.ISSN.1673-8799.2017.05.005

Hong-guang Zhu, Yu-xi Ge, G. Yan

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Abstract

Objective To investigate the distinct imaging features of different pathological subtypes of non-Hodgkin′s lymphomas(NHL)of the nose and pharynx and to improve its diagnostic accuracy. Methods A retrospective study was performed on the imaging materials(including CT or MRI)of 32 patients who were confirmed as NHL of the nose and pharynx by pathology.The materials were divided into two groups: NK/T cell lymphoma(NKTCL)and B cell lymphoma(BCL). The characteristics of the site, size, morphology, growth pattern, regional structure invasion of these lymphomas were evaluated and compared.The results were analyzed by Chi-quare test. Results A total of 12 cases(37.5%)were NK/T cell type, 10 cases(83.3%)mainly had nasal cavity involvement, 2 cases(16.7%)showed Waldeyer′s ring involvement, which were characterized by nasal soft tissue with mold growth.Among these, 7 cases(58.3%)had superficial ulcerations, 6 cases(50.0%)with regional structure invasion, 2 cases(16.7%)lymph node involvements.Besides, 20 cases(62.5%)were B cell type NHL.Among these, 19 cases(95.0%)had Waldeyer′s ring involvement and 1 case(5.0%)occurred in nasal cavity with pharyngeal lymphatic loop soft tissue incrassation, and 2 cases(16.7%)had regional structure involvement of pharyngeal space and bone.All cases showed cervical lymphadenopathy.Results of the Chi-square test showed that NKTCL had a higher incidence of nasal cavity involvement than B cell type NHL(χ2=20.401, P=0.000)and regional structure invasion (χ2=6.400, P=0.011), as well as superficial ulcerations (χ2=11.378, P=0.001). BCL had a higher incidence of Waldeyer′s ring involvement and creeping growth pattern(χ2=20.519, P=0.000), as well as lymphadenopathy(χ2=23.058, P=0.000)compared to NKTCL. Conclusion Primary NHLs of the nose and pharynx of different pathological subtypes has some characteristics on imaging, which may have supplementary value in the lymphoma diagnosis. Key words: Lymphoma; Pathological subtypes; MR; CT

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鼻咽部NK/T细胞型B细胞非霍奇金淋巴瘤不同病理亚型的影像学特征

目的探讨不同病理亚型鼻咽部非霍奇金淋巴瘤（NHL）的影像学特点，提高其诊断准确性。方法对32例经病理证实为鼻咽部NHL的患者的影像学资料（包括CT或MRI）进行回顾性分析。材料分为两组：NK/T细胞淋巴瘤（NKTCL）和B细胞淋巴瘤（BCL）。对这些淋巴瘤的部位、大小、形态、生长模式、区域结构侵犯等特点进行了评价和比较。结果用卡方检验进行分析。结果12例（37.5%）为NK/T细胞型，10例（83.3%）主要为鼻腔受累，2例（16.7%）为Waldeyer环受累，表现为鼻腔软组织伴霉菌生长。其中浅表溃疡7例（58.3%），局部结构侵犯6例（50.0%），淋巴结受累2例（16.7%）。B细胞型NHL 20例（62.5%），其中Waldeyer环受累19例（95.0%），鼻腔咽淋巴环软组织增厚1例（5.0%），咽间隙和骨区域结构受累2例（16.7%）。所有病例均表现为颈部淋巴结肿大。卡方检验结果显示，NKTCL鼻腔受累的发生率高于B细胞型NHL（χ2=20.401，P=0.000）、区域结构侵犯（χ2=6.400，P=0.011）和浅表溃疡（χ2=11.378，P=0.001），淋巴结肿大（χ2=23.058，P=0.000）。结论不同病理亚型的鼻咽部原发性非霍奇金淋巴瘤具有一定的影像学特征，对淋巴瘤的诊断有一定的辅助价值。关键词：淋巴瘤；病理亚型；MR；CT

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中国临床实用医学

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