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Nail toxicity with nail bed ulceration associated with pembrolizumab

IF 1.1 Q4 ALLERGY
Journal of Cutaneous Immunology and Allergy Pub Date : 2023-03-09 DOI:10.1002/cia2.12301
Shintaro Maeda MD, PhD, Yasuhito Hamaguchi MD, PhD, Kaori Sawada MD, PhD, Kyoko Shimizu MD, Kyosuke Oishi MD, PhD, Katsushige Taniuchi MD, PhD, Takashi Matsushita MD, PhD
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Abstract

A 70-year-old Japanese man was diagnosed with bladder cancer and started pembrolizumab. After six courses of pembrolizumab, all fingernails and toenails had fallen off and the nail beds were ulcerated. Pembrolizumab was discontinued, and he was treated with topical steroids and topical prostaglandin E1 ointment.

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pembrolizumab引起甲床溃疡的指甲毒性
一名 70 岁的日本男子被诊断出患有膀胱癌，并开始接受 pembrolizumab 治疗。使用 Pembrolizumab 六个疗程后，他的手指甲和脚趾甲全部脱落，甲床溃烂。他停用了 Pembrolizumab，并接受了局部类固醇和局部前列腺素 E1 软膏治疗。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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来源期刊
Journal of Cutaneous Immunology and Allergy
Journal of Cutaneous Immunology and Allergy Medicine-Dermatology
CiteScore
0.60
自引率
10.00%
发文量
69
审稿时长
12 weeks
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