{"title":"What is the role of post acute EEG in prediction of late neurological outcome in severe disorders of consciousness?","authors":"M. Scarpino, F. Lolli, G. Lanzo, A. Grippo","doi":"10.2217/fnl-2019-0017","DOIUrl":null,"url":null,"abstract":"Causes of development of severe disorders of consciousness Hypoxic-ischemic encephalopathy, traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage and brain infarction are common causes of mortality and morbidity [1–8]. Many patients affected by these acquired brain injuries (ABIs) die in the acute stages during their stay in the intensive care unit; others, after a coma phase, usually develop a severe disorder of consciousness (DoC), characterized by an unresponsive wakefulness syndrome or a minimally conscious state (MCS). In some cases, consciousness level improves, transitioning to an emergence from MCS (E-MCS); however, patients with E-MCS often show a severe neurological disability [9]. In recent years, improvements both in intensive care technology and in neurosurgical procedures have reduced the mortality rate; however, as a result, many patients discharged from the acute setting exhibit severe DoCs.","PeriodicalId":12606,"journal":{"name":"Future Neurology","volume":" ","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/fnl-2019-0017","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/fnl-2019-0017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 1
Abstract
Causes of development of severe disorders of consciousness Hypoxic-ischemic encephalopathy, traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage and brain infarction are common causes of mortality and morbidity [1–8]. Many patients affected by these acquired brain injuries (ABIs) die in the acute stages during their stay in the intensive care unit; others, after a coma phase, usually develop a severe disorder of consciousness (DoC), characterized by an unresponsive wakefulness syndrome or a minimally conscious state (MCS). In some cases, consciousness level improves, transitioning to an emergence from MCS (E-MCS); however, patients with E-MCS often show a severe neurological disability [9]. In recent years, improvements both in intensive care technology and in neurosurgical procedures have reduced the mortality rate; however, as a result, many patients discharged from the acute setting exhibit severe DoCs.
期刊介绍:
The neurological landscape is changing rapidly. From the technological perspective, advanced molecular approaches and imaging modalities have greatly increased our understanding of neurological disease, with enhanced prospects for effective treatments in common but very serious disorders such as stroke, epilepsy, multiple sclerosis and Parkinson’s disease. Nevertheless, at the same time, the healthcare community is increasingly challenged by the rise in neurodegenerative diseases consequent upon demographic changes in developed countries.