Antibacterial efficacy of the combination of triphala and chlorhexidine mouthwashes on salivary Streptococcus mutans of orthodontic patients: A randomized clinical trial

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of International Oral Health Pub Date : 2022-11-01 DOI:10.4103/jioh.jioh_64_22

Amir Hooman Sadr Haghighi, Raana Sarvari, H. Eslami, E. Fakhri, Roghayeh Nouri, Arezou Karimzadeh Sureshjani

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Abstract

Aim: The aim of this study was to compare and evaluate the antibacterial efficacy of triphala mouthwash and its combination with 0.2% chlorhexidine against salivary Streptococcus mutans of orthodontic patients. Materials and Methods: A total of 54 patients under fixed orthodontic therapy were included in this randomized clinical trial and divided into three groups of 18 each. The groups were requested to use one of three mouthwashes two times a day for 10 days: chlorhexidine 0.2%, triphala 25%, and the combination of chlorhexidine and triphala (1:1). Saliva samples were collected at baseline (day 0) and after 10 days. Ultimately, the samples were diluted and cultured. After incubation, the formed colonies were counted and the CFU/mL was calculated. The results were analyzed statistically with one-way analysis of variance and t test. Results: All mouthwashes decreased the bacterial count from baseline to the end of 10 days (P < 0.05). Although triphala had the least antimicrobial effect, no significant difference was observed between the chlorhexidine and the combined mouthwash group (P = 0.251). Conclusion: It was concluded that the combination of chlorhexidine and triphala reduces the side effects of chlorhexidine while presenting an acceptable antibacterial efficacy.

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三宝和氯己定联合漱口液对正畸患者唾液变形链球菌的抗菌效果：一项随机临床试验

目的：本研究旨在比较和评价三帕拉漱口水及其与0.2%氯己定联合使用对正畸患者唾液变形链球菌的抗菌效果。材料和方法：本随机临床试验共纳入54例接受固定正畸治疗的患者，分为三组，每组18例。两组被要求使用三种漱口水中的一种，每天两次，持续10天：0.2%的氯己定、25%的三帕拉，以及氯己定和三帕拉的组合（1:1）。在基线（第0天）和10天后采集唾液样本。最后，对样品进行稀释和培养。培养后，对形成的菌落进行计数，并计算CFU/mL。采用单因素方差分析和t检验对结果进行统计学分析。结果：从基线到10天，所有漱口水的细菌计数均下降（P<0.05），结论：洗必泰与三苯氧胺联合应用可减少洗必泰的副作用，同时具有可接受的抗菌效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of International Oral Health Dentistry-Dentistry (all)

CiteScore

1.00

自引率

14.30%

发文量

期刊介绍： It is a journal aimed for research, scientific facts and details covering all specialties of dentistry with a good determination for exploring and sharing the knowledge in the medical and dental fraternity. The scope is therefore huge covering almost all streams of dentistry - starting from original studies, systematic reviews, narrative reviews, very unique case reports. Our journal appreciates research articles pertaining with advancement of dentistry. Journal scope is not limited to these subjects and is more wider covering all specialities of dentistry follows: Preventive and Community Dentistry (Dental Public Health) Endodontics Oral and Maxillofacial Pathology Oral and Maxillofacial Radiology Oral and Maxillofacial Surgery (also called Oral Surgery) Orthodontics and Dentofacial Orthopaedics Periodontology (also called Periodontics) Pediatric Dentistry (also called Pedodontics) Prosthodontics (also called Prosthetic Dentistry) Oral Medicine Special Needs Dentistry (also called Special Care Dentistry) Oral Biology Forensic Odontology Geriatric Dentistry or Geriodontics Implantology Laser and Aesthetic Dentistry.