Chemistry of Medicinally important Dihydropyrimidinone-based Heterocycle Scaffolds

Abstract

In medicinal chemistry, Dihydropyrimidinone-based heterocycle scaffolds have attained a prominent place due to their enormous pharmacological and biological activities. The discovery and development of innovative drugs to combat a wide range of diseases exemplify the utility of these compounds. The present study summarizes the variety of methods available to synthesize various dihydropyrimidinone-based heterocycle scaffolds and their beneficial medicinal properties with the available literature until 2022.