Photoprotective Activity of Plants Used for Skin Disorders by the Native Population from the Brazilian Amazon Basin: A Preliminary Study

IF 0.7 Q4 PHARMACOLOGY & PHARMACY

Pharmacognosy Research Pub Date : 2022-12-15 DOI:10.5530/097484900267

T. Portal, M. Tavares, Marcieni Ataide, N. R. Barbosa, Joseane R da Silva, Waldinei P Moraes, José L. Vieira

{"title":"Photoprotective Activity of Plants Used for Skin Disorders by the Native Population from the Brazilian Amazon Basin: A Preliminary Study","authors":"T. Portal, M. Tavares, Marcieni Ataide, N. R. Barbosa, Joseane R da Silva, Waldinei P Moraes, José L. Vieira","doi":"10.5530/097484900267","DOIUrl":null,"url":null,"abstract":"Background: Sunscreens are essential in tropical countries with a high annual incidence of solar radiation. The incorporation of natural products in their formulations has great public acceptance and prevents several issues related to organic and inorganic filters, such as adverse reactions. The present study evaluates the antioxidant and photoprotective activities and the ability to inhibit tyrosinase of three plant species traditionally used by Amazonian inhabitants in the treatment of skin disorders. Materials and Methods: The antioxidant activity, the capacity to inhibit the enzyme tyrosinase, ratio UVA/UVB, critical wavelength, sun protection factor, and cellular viability was assessed in ethanolic extracts at 10% of Chrysobalanus icaco, Kalanchoe pinnata , and Ayapana triplinervis collected in the State of Para-Brazil. Results: Chrysobalanus icaco and Kalanchoe pinnata showed promising antioxidant activity. Ayapana triplinervis demonstrated considerable inhibition of the tyrosinase enzyme. Plants extracts had low protection against UVB radiation, but adequate UVA protection. Ayapana triplinervis presented the lowest cellular viability of keratinocytes and murine fibroblasts. Conclusion: The addition of these extracts to other natural products with high sun protection factors can provide the consumer with a natural sunscreen.","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacognosy Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5530/097484900267","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}

引用次数: 1

Abstract

Background: Sunscreens are essential in tropical countries with a high annual incidence of solar radiation. The incorporation of natural products in their formulations has great public acceptance and prevents several issues related to organic and inorganic filters, such as adverse reactions. The present study evaluates the antioxidant and photoprotective activities and the ability to inhibit tyrosinase of three plant species traditionally used by Amazonian inhabitants in the treatment of skin disorders. Materials and Methods: The antioxidant activity, the capacity to inhibit the enzyme tyrosinase, ratio UVA/UVB, critical wavelength, sun protection factor, and cellular viability was assessed in ethanolic extracts at 10% of Chrysobalanus icaco, Kalanchoe pinnata , and Ayapana triplinervis collected in the State of Para-Brazil. Results: Chrysobalanus icaco and Kalanchoe pinnata showed promising antioxidant activity. Ayapana triplinervis demonstrated considerable inhibition of the tyrosinase enzyme. Plants extracts had low protection against UVB radiation, but adequate UVA protection. Ayapana triplinervis presented the lowest cellular viability of keratinocytes and murine fibroblasts. Conclusion: The addition of these extracts to other natural products with high sun protection factors can provide the consumer with a natural sunscreen.

查看原文本刊更多论文

巴西亚马逊流域土著群体用于皮肤疾病的植物的光保护活性：初步研究

背景：在每年太阳辐射发生率高的热带国家，防晒霜是必不可少的。在配方中加入天然产品得到了公众的广泛接受，并防止了与有机和无机过滤器有关的一些问题，如不良反应。本研究评估了亚马逊居民传统上用于治疗皮肤疾病的三种植物的抗氧化和光保护活性以及抑制酪氨酸酶的能力。材料和方法：在Para Brazil州收集的10%的金龟子、羽扇菜和Ayapana三倍体乙醇提取物中评估抗氧化活性、抑制酪氨酸酶的能力、UVA/UVB比率、临界波长、防晒因子和细胞活力。结果：金龟子和羽扇菜具有良好的抗氧化活性。Ayapana三倍体对酪氨酸酶表现出相当大的抑制作用。植物提取物对UVB辐射的防护能力较低，但对UVA的防护能力足够。Ayapana三倍体表现出角质形成细胞和小鼠成纤维细胞的最低细胞活力。结论：将这些提取物添加到其他具有高防晒因子的天然产品中，可以为消费者提供天然防晒霜。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pharmacognosy Research PHARMACOLOGY & PHARMACY-

自引率

14.30%

发文量

期刊介绍： Pharmacognosy Research [ISSN: Print -0976-4836, Online - 0974-8490] [http://www.phcogres.com], Quarterly a publication of Phcog.Net is published by Wolters Kluwer - Medknow Publications. It provides peer-reviewed original research articles from the field of Natural Products. The journal serves an international audience of scientists and researchers in a variety of research and academia by quickly disseminating research findings related to Medicinal Plants and Natural Products. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submissions of original contributions in all areas of pharmacognosy are welcome.