A paraneoplastic optic neuropathy revealing a pulmonary epidermal carcinoma

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Y. Mouzari, I. Fiqhi, Belfaiza Soukaina, T. Abdellaoui, M. Allaoui, K. Reda, A. Oubaaz
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引用次数: 0

Abstract

Paraneoplastic optic neuropathy is a relatively rare ocular manifestation. We report the case of a patient with bilateral papilledema revealing a pulmonary squamous cell carcinoma. Paraneoplastic neuropathy is linked to an immune reaction by the presence of autoantibodies against collapsin responsive mediator protein 5 . Diagnosis is based on the determination of these autoantibodies and the search for occult cancer by PET scan.Treatment is often based on corticosteroid therapy and sometimes immunosuppressive treatment is necessary in the case of corticosteroid unresponsiveness.
副肿瘤性视神经病变显示肺表皮癌
副肿瘤性视神经病变是一种相对罕见的眼部表现。我们报告了一例双侧视乳头水肿的患者,显示为肺鳞状细胞癌。副肿瘤性神经病与免疫反应有关,这是由于存在抗组织蛋白酶反应介质蛋白5的自身抗体。诊断是基于这些自身抗体的测定和通过PET扫描寻找隐性癌症。治疗通常基于皮质类固醇治疗,有时在皮质类固醇无反应的情况下需要免疫抑制治疗。
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来源期刊
Indian Journal of Medical Specialities
Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-
自引率
16.70%
发文量
51
期刊介绍: The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.
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