Promising antioxidant activity of crude extract from Calliandra tweedii Benth

Kátia Pereira dos Santos, Alice Nagai, Carmen E. Palacios, Bruno Evangelista, Carlos Pri̇ante, Débora Zamban, C. Furlan
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引用次数: 0

Abstract

The interest in medicinal plants encourages new research studies on plant extracts, as they are sources for treatments in medicine, agriculture, and veterinary. Calliandra tweedii is a native Brazilian species with broad use in folk medicine. This study aimed to examine the leaf crude extract (CE) of C. tweedii and its methanolic (MP) and hexane (HP) phases concerning total phenolic compounds (TPC), proanthocyanidins (PRO), and flavonoid profile, and correlate it to their antioxidant activity (DPPH and FRAP). CE and MP revealed high contents of TPC, PRO and high antioxidant activity (DPPH and FRAP) in relation to HP. Opposite, HP showed reduced antioxidant activity, according to the scarce phenolic constituents obtained from the partition. Five flavonols were detected by HPLC-UV-DAD, being quercitrin the major constituent. Also, one kaempferol derivate, and a series of three quercetin derivates were detected. Strong positive correlations were observed between DPPH, FRAP, and phenolic compounds. These discoveries are important to highlight the promising antioxidant activity of CE of C. tweedii, which could contribute to the expansion of popular herbal medicines and new drug discovery.
杜鹃花粗提物抗氧化活性研究
对药用植物的兴趣鼓励了对植物提取物的新研究,因为它们是医学、农业和兽医治疗的来源。特威迪卡利安德拉是一种巴西本土物种,在民间医学中有着广泛的用途。本研究旨在检测粗花叶提取物(CE)及其甲醇(MP)和己烷(HP)相的总酚类化合物(TPC)、原花青素(PRO)和类黄酮含量,并将其与抗氧化活性(DPPH和FRAP)联系起来。CE和MP显示与HP相关的TPC、PRO含量高和抗氧化活性高(DPPH和FRAP)。相反,根据从分配中获得的稀缺酚类成分,HP显示出降低的抗氧化活性。用HPLC-UV-DAD法检测了5种黄酮醇,其中槲皮素为主要成分。此外,还检测到一种山奈酚衍生物和一系列三种槲皮素衍生物。DPPH、FRAP和酚类化合物之间存在很强的正相关性。这些发现对于突出粗花C.tweedii CE的抗氧化活性具有重要意义,这可能有助于扩大流行草药和新药的发现。
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来源期刊
International Journal of Secondary Metabolite
International Journal of Secondary Metabolite Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
1.40
自引率
0.00%
发文量
28
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