Evaluating The Effects of Traditional Herbal Medicine X-911 on Cytokine Expression and Glucose Uptake in LL2 Cells With 18F-FDG/MicroPET

Abstract

Traditional Chinese medicine (TCM) is empirically based, with a history of over 4000 years, and is used widely in China, Japan, Korea, Singapore, and elsewhere [1]. In TCM, the biological ingredients of herbal remedies are extracted from natural substances: plants, animal parts, shells, insects, and even stones and minerals. TCM is commonly used to nourish the blood, activate circulation, alleviate pain, regulate menstruation and attack tumor tissues, alone or in combination with anticancer drugs [2]. TCM can be used in cancer prophylaxis and/or treatment, for example, as Phyllanthus urinaria protects the liver from hepatocarcinogenesis and has shown anticancer activity [3]. Sho-saiko-to has hepatoprotective effects in various liver injury experiments, including the injury induced with CCl4 and D-galactosamine [4,5]. Paeoniae radix (PR) improves blood flow by its endothelium-dependent vasodilator action and potential antiaging and anticarcinogenesis activities [6].