A retrospective study comparing the efficiency of recurrent LSIL cytology to high-grade cytology as predictors of high-grade cervical intraepithelial neoplasia or worse (CIN2+)

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Southern African Journal of Gynaecological Oncology Pub Date : 2021-08-12 DOI:10.1080/20742835.2021.1962020

R. Suleman, M. Botha

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Abstract

Background Cervical cancer (CC) is one of the most preventable cancers; however, it is the leading cause of cancer-related female deaths in South Africa. This study aimed to compare the efficiency of recurrent low-grade squamous intraepithelial lesion (LSIL) cytology as criteria to predict CIN2+ incidence, to a single initial high-grade squamous intraepithelial lesion (HSIL) cytology. Methods A retrospective cohort study comprising 344 women was conducted from January 2014 to December 2018 at the Colposcopy Clinic, Tygerberg Hospital. The women were categorised into two groups: (1) women with a recurrent LSIL cytology result, with recurrent cytology scheduled within 6–12 months; (2) women diagnosed with a single initial HSIL cytology result. The outcome was dichotomised into (1) normal or cervical intraepithelial neoplasia 1 (

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一项回顾性研究比较复发性LSIL细胞学与高级别细胞学作为高级别宫颈上皮内瘤变或更严重(CIN2+)预测指标的效率

宫颈癌是最容易预防的癌症之一;然而，它是南非女性癌症相关死亡的主要原因。本研究旨在比较复发性低级别鳞状上皮内病变(LSIL)细胞学作为预测CIN2+发病率的标准与单一初始高级别鳞状上皮内病变(HSIL)细胞学的效率。方法对2014年1月至2018年12月在泰格伯格医院阴道镜门诊就诊的344名女性进行回顾性队列研究。这些女性被分为两组:(1)有复发性低级别鳞状细胞癌细胞学检查结果的女性，在6-12个月内进行复发性细胞学检查;(2)诊断为单一HSIL初始细胞学结果的女性。结果分为(1)正常或宫颈上皮内瘤变1 (

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