Sequential estimation of creatinine removal by a haemodialyser

IF 1.1 4区工程技术 Q3 ENGINEERING, MULTIDISCIPLINARY

Inverse Problems in Science and Engineering Pub Date : 2021-03-11 DOI:10.1080/17415977.2021.1897123

Felipe Y. Magalhães, H. Orlande, J. Suassuna

引用次数: 0

Abstract

This work is focused on the transient analysis of a haemodialyser. The objective is to sequentially estimate the concentration of creatinine in the blood returning to the patient, by solving a state estimation problem with measurements of the outflow creatinine concentration in the dialysate. Simulated measurements containing Gaussian errors were used in the inverse analysis, which was based on the Sampling Importance Resampling (SIR) algorithm of the Particle Filter method. Accurate results reveal that this technique may possibly be used for online monitoring and control of the haemodialysis therapy.

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血液透析器去除肌酸酐的顺序估计

这项工作的重点是血液透析的瞬态分析。目的是通过测量透析液中流出肌酸酐浓度来解决状态估计问题，从而依次估计返回患者血液中的肌酸酐浓度。基于粒子滤波方法中的采样重要性重采样(SIR)算法，利用含有高斯误差的模拟测量值进行反分析。准确的结果表明，该技术可能用于血液透析治疗的在线监测和控制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Inverse Problems in Science and Engineering 工程技术-工程：综合

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Inverse Problems in Science and Engineering provides an international forum for the discussion of conceptual ideas and methods for the practical solution of applied inverse problems. The Journal aims to address the needs of practising engineers, mathematicians and researchers and to serve as a focal point for the quick communication of ideas. Papers must provide several non-trivial examples of practical applications. Multidisciplinary applied papers are particularly welcome. Topics include: -Shape design: determination of shape, size and location of domains (shape identification or optimization in acoustics, aerodynamics, electromagnets, etc; detection of voids and cracks). -Material properties: determination of physical properties of media. -Boundary values/initial values: identification of the proper boundary conditions and/or initial conditions (tomographic problems involving X-rays, ultrasonics, optics, thermal sources etc; determination of thermal, stress/strain, electromagnetic, fluid flow etc. boundary conditions on inaccessible boundaries; determination of initial chemical composition, etc.). -Forces and sources: determination of the unknown external forces or inputs acting on a domain (structural dynamic modification and reconstruction) and internal concentrated and distributed sources/sinks (sources of heat, noise, electromagnetic radiation, etc.). -Governing equations: inference of analytic forms of partial and/or integral equations governing the variation of measured field quantities.