AKTIVITAS ANTIMALARIA SENYAWA FLAVANON TERISOPRENILASI DARI KULIT BATANG Erythrina fusca L.

Abstract

Two isoprenylated flavanones  namely as lonchocarpol A (1)  dan lupinifolin (2) were isolated from  the stem bark of Limonia accidissima L. Erythrina fusca L. Their structures were determined  based on spectroscopic data such as UV, IR, MS and NMR. Compounds 1–2 were evaluated for their antimalarial against Plasmodium falciparum strain 3D7 showing their IC50 were 1.18 and 0.8 µg/ml, respectively and very high activity.