Value of pathogenic diagnosis of 18F-FDG PET/CT imaging in non-traumatic unilateral vocal cord paralysis

中华核医学与分子影像杂志 Pub Date : 2020-01-25 DOI:10.3760/CMA.J.ISSN.2095-2848.2020.01.004

Jiong Zheng

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引用次数: 0

Abstract

Objective To evaluate the diagnostic value of 18F-fluorodeoxyglucose (FDG) PET/CT imaging in non-traumatic unilateral vocal cord paralysis (UVCP) and compare the radioactive uptake in different lesions. Methods Clinical data of 62 patients (49 males, 13 females; age: (61.7±12.8) years) with non-traumatic UVCP (43 cases of left vocal cord paralysis and 19 cases of right) admitted to Ji′an Hospital from January 2016 to December 2018 were analyzed retrospectively. Pathological results, imaging or follow-up results were considered as the standard of final diagnosis. The diagnostic efficacy of PET/CT imaging for the primary cause was analyzed. The maximum standardized uptake values (SUVmax) of vocal cord in patients with different etiology were compared by independent-sample t test. Results According to the final diagnosis, the primary causes of UVCP were as follows: malignant tumors (n=44), inflammation (n=16), glomus jugulare tumor (n=1) and idiopathic UVCP (n=1). The diagnostic accuracy of PET/CT imaging for the primary cause was 90.32%(56/62): 44 cases were correctly diagnosed as malignant tumors, while 11 cases as inflammation, and 1 case as glomus jugulare tumor. Among 62 patients, 29 patients had increased SUVmax in the affected side (direct invasion group; further divided into tumor group (n=12) and non-tumor group (n=17)), and other 33 patients had increased SUVmax in the healthy side (indirect invasion group). SUVmax of the affected vocal cord in direct invasion group was higher than that in the healthy side (9.97±5.21 vs 2.43±0.62; t=8.14, P 0.05). Conclusions 18F-FDG PET/CT imaging has high diagnostic value in pathogenic diagnosis of non-traumatic UVCP. The different radioactive uptake of vocal cords in the affected side and the healthy side provides more accurate etiological information for clinical analysis. Key words: Vocal cord paralysis; Positron-emission tomography; Tomography, X-ray computed; Deoxyglucose

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18F-FDG PET/CT显像对非创伤性单侧声带麻痹的病因诊断价值

目的探讨18f -氟脱氧葡萄糖(FDG) PET/CT对非外伤性单侧声带麻痹(UVCP)的诊断价值，并比较不同病变的放射性摄取情况。方法62例患者的临床资料(男49例，女13例;回顾性分析2016年1月至2018年12月吉安医院收治的非外伤性UVCP患者(61.7±12.8)岁，其中左声带麻痹43例，右声带麻痹19例。病理结果、影像学或随访结果作为最终诊断的标准。分析PET/CT对主要病因的诊断效果。采用独立样本t检验比较不同病因患者声带最大标准化摄取值(SUVmax)。结果经最终诊断，UVCP的主要病因为:恶性肿瘤44例，炎症16例，颈静脉球瘤1例，特发性UVCP 1例。PET/CT对原发病因的诊断正确率为90.32%(56/62)，其中恶性肿瘤44例，炎症11例，颈静脉球瘤1例。62例患者中，29例患者患侧SUVmax增高(直接侵袭组;进一步分为肿瘤组(n=12)和非肿瘤组(n=17)，其余33例患者在健康侧(间接侵袭组)出现SUVmax增高。直接侵犯组患声带SUVmax高于健侧组(9.97±5.21 vs 2.43±0.62);t=8.14, p0.05)。结论18F-FDG PET/CT在非外伤性UVCP的病因诊断中具有较高的诊断价值。患侧和健康侧声带放射性摄取的差异为临床分析提供了更准确的病因信息。关键词:声带麻痹;正电子发射断层扫描;断层扫描，x射线计算机;脱氧葡萄糖

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来源期刊

中华核医学与分子影像杂志核医学，分子影像

自引率

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发文量

5088

期刊介绍： Chinese Journal of Nuclear Medicine and Molecular Imaging (CJNMMI) was established in 1981, with the name of Chinese Journal of Nuclear Medicine, and renamed in 2012. As the specialized periodical in the domain of nuclear medicine in China, the aim of Chinese Journal of Nuclear Medicine and Molecular Imaging is to develop nuclear medicine sciences, push forward nuclear medicine education and basic construction, foster qualified personnel training and academic exchanges, and popularize related knowledge and raising public awareness. Topics of interest for Chinese Journal of Nuclear Medicine and Molecular Imaging include: -Research and commentary on nuclear medicine and molecular imaging with significant implications for disease diagnosis and treatment -Investigative studies of heart, brain imaging and tumor positioning -Perspectives and reviews on research topics that discuss the implications of findings from the basic science and clinical practice of nuclear medicine and molecular imaging - Nuclear medicine education and personnel training - Topics of interest for nuclear medicine and molecular imaging include subject coverage diseases such as cardiovascular diseases, cancer, Alzheimer’s disease, and Parkinson’s disease, and also radionuclide therapy, radiomics, molecular probes and related translational research.