Screening and analysis of the serum thyroid stimulating hormone (TSH) of rural pregestational women In Yunnan province

Q4 Medicine

中华内分泌代谢杂志 Pub Date : 2019-11-25 DOI:10.3760/CMA.J.ISSN.1000-6699.2019.11.008

Z-W Xie, Genrui Li, Juanjuan Chen, Hong Sun, G. Cao

{"title":"Screening and analysis of the serum thyroid stimulating hormone (TSH) of rural pregestational women In Yunnan province","authors":"Z-W Xie, Genrui Li, Juanjuan Chen, Hong Sun, G. Cao","doi":"10.3760/CMA.J.ISSN.1000-6699.2019.11.008","DOIUrl":null,"url":null,"abstract":"Objective \nThrough screening the serum TSH in rural pregestational women, fo find out the high incidence area and high risk population of thyroid disease in Yunnan province, to reduce the probability of infertility and abnormal pregnancy and provide important reference basis for prenatal aristogenesis. \n \n \nMethods \nThe serum TSH level of 30 163 rural pregestational women(20-49 yeas old) which from 16 different areas and 16 different ethnicities of Yunnan province was detected by using TSH3-Ultra (TSH3-UL) reagent on a Siemens centar-XP automatic chemiluminescence apparatus. \n \n \nResults \n1 797 women were found with abnormal serum TSH level, the abnormal rate was 5.96%. Among them, the proportion of women with decreased TSH was 3.09% and increased TSH was 2.87%, compared with the normal reference range. And there was a significant difference of abnormal serum TSH rate between pregestational women from different areas and ethnicities. Moreover, in the 16 tested areas, the highest abnormal serum TSH rate was 8.90% from Ximeng county, the lowest was 3.60% from Diqing state. However in the 16 tested ethnicities, the highest abnormal serum TSH rate was 9.73% from Lisu ethnic minority and the lowest was 3.60% from Tibetan ethnic minority. \n \n \nConclusions \nThe results inferred that ethnic and regional factors both to some extent affect the prevalence of thyroid disease in pregestational women and it is a small probability event that high occurrence of TSH decreased or increased situation simultaneously happened in one area or one ethnicity. \n \n \nKey words: \nThyroid stimulating hormone; Pregestational Women; Rural areas; Minority of Yunnan Province","PeriodicalId":10120,"journal":{"name":"中华内分泌代谢杂志","volume":"35 1","pages":"962-968"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华内分泌代谢杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1000-6699.2019.11.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objective Through screening the serum TSH in rural pregestational women, fo find out the high incidence area and high risk population of thyroid disease in Yunnan province, to reduce the probability of infertility and abnormal pregnancy and provide important reference basis for prenatal aristogenesis. Methods The serum TSH level of 30 163 rural pregestational women(20-49 yeas old) which from 16 different areas and 16 different ethnicities of Yunnan province was detected by using TSH3-Ultra (TSH3-UL) reagent on a Siemens centar-XP automatic chemiluminescence apparatus. Results 1 797 women were found with abnormal serum TSH level, the abnormal rate was 5.96%. Among them, the proportion of women with decreased TSH was 3.09% and increased TSH was 2.87%, compared with the normal reference range. And there was a significant difference of abnormal serum TSH rate between pregestational women from different areas and ethnicities. Moreover, in the 16 tested areas, the highest abnormal serum TSH rate was 8.90% from Ximeng county, the lowest was 3.60% from Diqing state. However in the 16 tested ethnicities, the highest abnormal serum TSH rate was 9.73% from Lisu ethnic minority and the lowest was 3.60% from Tibetan ethnic minority. Conclusions The results inferred that ethnic and regional factors both to some extent affect the prevalence of thyroid disease in pregestational women and it is a small probability event that high occurrence of TSH decreased or increased situation simultaneously happened in one area or one ethnicity. Key words: Thyroid stimulating hormone; Pregestational Women; Rural areas; Minority of Yunnan Province

查看原文本刊更多论文

云南省农村育龄妇女血清促甲状腺激素的筛查与分析

目的通过对云南省农村妊娠妇女血清TSH的筛查，找出云南省甲状腺疾病的高发地区和高危人群，降低不孕和异常妊娠的概率，为产前优生提供重要参考依据。方法采用TSH3-Ultra (TSH3-UL)试剂，在西门子centar-XP型自动化学发光仪上对云南省16个不同地区、16个不同民族的30 163例农村孕妇(20 ~ 49岁)血清TSH水平进行检测。结果1 797例妇女血清TSH异常，异常率为5.96%。其中，与正常参考范围相比，TSH下降的比例为3.09%，TSH升高的比例为2.87%。不同地区、不同民族孕妇血清TSH异常率差异有统计学意义。16个检测地区中，西蒙县TSH异常率最高，为8.90%，迪庆州最低，为3.60%。16个民族中，傈僳族血清TSH异常率最高，为9.73%，藏族最低，为3.60%。结论民族和地区因素均对妊娠妇女甲状腺疾病的发生有一定的影响，在一个地区或一个民族同时发生高TSH降低或升高的情况是小概率事件。关键词:促甲状腺激素;孕前的女性;农村地区;云南少数民族

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

中华内分泌代谢杂志 Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

0.60

自引率

0.00%

发文量

7243

期刊介绍： The Chinese Journal of Endocrinology and Metabolism was founded in July 1985. It is a senior academic journal in the field of endocrinology and metabolism sponsored by the Chinese Medical Association. The journal aims to be the "Chinese broadcaster of new knowledge on endocrinology and metabolism worldwide". It reports leading scientific research results and clinical diagnosis and treatment experience in endocrinology and metabolism and related fields, as well as basic theoretical research that has a guiding role in endocrinology and metabolism clinics and is closely integrated with clinics. The journal is a core journal of Chinese science and technology (a statistical source journal of Chinese science and technology papers), and is included in Chinese and foreign statistical source journal databases such as the Chinese Science and Technology Papers and Citation Database, Chemical Abstracts, and Scopus.