Correlation of Parkinson’s disease with diabetes mellitus, obesity, dyslipidemia and their association with severity of disease

Abstract

Introduction. The present study aimed to investigate Parkinson’s disease with diabetes, obesity, dyslipidemia and their relationship with disease severity. Methods. In this case-control study, all patients referred to Rouhani Hospital in Babol with clinical diagnosis of Parkinson’s disease were excluded in the case study and the control group was selected from the patients of the clinic and neurology ward. Parkinson’s disease diagnosis was based on common criteria and the four classic sign (symptoms) of the disease. Results. Obesity in patients with Parkinson’s disease was 65.4%, which was higher than the control group with 34.6%. The association between obesity and Parkinson’s disease was significant (OR = 2.14 and p = 0.01). Diabetes was 59.7% in patients with Parkinson’s disease and was 40.3% in patients in the control group that diabetes is also associated with the incidence of Parkinson’s disease (OR = 2.59 and p <0.001). 59.6% of patients with Parkinson’s disease had anemia, while 40.4% of the control group had anemia, and the relationship between anemia and Parkinson’s disease was significant (OR = 1.78 and p = 0.02). 55.5% of patients with Parkinson’s disease had dyslipidemia, while 44.5% of the control group had dyslipidemia, and the relationship between dyslipidemia and Parkinson’s disease was significant (OR = 2.09 and p = 0.004). Conclusion. In summary, this study showed that Parkinson’s is associated with obesity, diabetes, anemia and dyslipidemia. The above cases were effective as risk factors for Parkinson’s disease and how it requires further research in this area.