Pattern of Changes in Papanicolaou Smears for Patients Visiting Alwazart PHC, Riyadh, Saudi Arabia

Alanoud Aldrees, Aljoharah Alosaimy, Mostafa Kofi
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Abstract

Tests such as the Papanicolaou smear are considered the gold standard for cervical cancer screening, which is available in almost every public health center and very effective in early detection of malignant or even premalignant lesion. Aim: Promote early detection of changes in pap smears and improve services in well women health clinics. Methods: This descriptive cross-section study was conducted in Alwazart primary healthcare center, Riyadh, Saudi Arabia for all women whose age above 21, and pap smear test done in July 2015-July 2020 were included. Results: In our study, pathological cervical cell changes begin at an earlier age, with atypical squamous cells of undetermined significance starting at a median age of 28. Nonetheless, low grade squamous interepithelial lesions were common in 35-year-olds. Atypical glandular cells and low grade squamous intraepithelial lesions were found in 1.4% of Pap smears. The median age of the study group was 44.88. Conclusion: Pap smears in our community show abnormal cellular changes at an earlier age. The most effective preventive methods for cervical cancer are routine screening and vaccination against HPV.
沙特阿拉伯利雅得Alwazart PHC患者Papanicolaou涂片变化模式
巴氏涂片等检查被认为是癌症筛查的金标准,几乎每个公共卫生中心都可以使用,在早期发现恶性甚至癌前病变方面非常有效。目的:促进早期发现巴氏涂片的变化,改善妇女健康诊所的服务。方法:这项描述性横断面研究在沙特阿拉伯利雅得的Alwazart初级保健中心对所有21岁以上的女性进行,并纳入2015年7月至2020年7月进行的巴氏涂片检查。结果:在我们的研究中,病理性宫颈细胞变化始于更早的年龄,不典型鳞状细胞的重要性尚未确定,始于中位年龄28岁。尽管如此,低级别鳞状上皮间病变在35岁的人群中很常见。在1.4%的巴氏涂片中发现非典型腺细胞和低级别鳞状上皮内病变。研究组的中位年龄为44.88岁。结论:我们社区的巴氏涂片在早期显示出异常的细胞变化。宫颈癌症最有效的预防方法是常规筛查和接种HPV疫苗。
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