The efficiency of the correction of metabolism and normalization of reproductive function of cows with the use of modified iodinol

Abstract

The article presents theoretical substantiation for injecting a iodometabolic composition based on the well-known veterinary preparation iodinol in combination with succinic acid to correct pathobiochemical precesses of highly productive cows. Until recently injection method of the preparation administration in clinical veterinary medicine has not been considered and is not practiced/ The main deterrent was the old regulations that only regulated the external ana oral use of the preparation. More recently the possibility of injecting iodinol to accelerate the recovery of reproductive function in cows was successfully implemented in the dissertation study of Vitol V.A. (2010). The modification of iodinol with the inclusion of the hepatoprotector succunic acid as a strong metabolic is even more promising for its use in infectious and non-infectious pathology. In our research the injectable method of using iodinol in a complex with succinic acid was tested on highly productive cows during intensive endogenous lipolysis with well- expressed symptoms of metabolic acidosis, ketoacidosis, a high risk of developing fatty hepatosis and an unfavorable prognosis of practical use, According to the results of clinical studies it was found out that the cows of the first experimental group in which iodinol was tested in combination with succinic acid, protein content, total lipids, cholesterol, and glucose were already within the average physiological values on the 15th day. This indicated that energy processes of fat oxidation in the liver began to proceed without any deviations. Actually this is evidenced by the low levels of ketone bodies. On the contrary, the use of pharmacopeic iodinol in the second group did not have such a pronounced metabolic effect. In the animals of this group all biochemical parameters were either lower (glucose) or higher (total lipids, total bilirubin, cholesterol, ketone bodies, ASAT and ALAT transamination enzymes) than physiological values. This had a positive impact on the health of cows and the restoration of their reproductive ability. Within 60 days of lactation period the indicators of the cows disposal were as follows: 3 (3.5 %) in the first group of 83 cows, 9 (10.7 %) in the second group of 84, and 25 (25.5 %) in the third (control) group of 98 animals. Thus, a technologically simple approach to correcting metabolism with the availability and environmental safety of the components can reduce the severity of the problem of ensuring the health of high-yielding cows.