A Forecast of Targeting Leukemia Stem Cells by Nanomedicine

Abstract

Leukemia Stem Cells (LSCs) are a subpopulation of leukemic cells that display characteristics of self-renewal, differentiation and tumor-initiating capacity. They are also thought to be responsible for Chemoradiotherapy resistance and the recurrence of leukemia. Recently, Nanomedicine has been widely used for cancer treatments with improved targeting efficiency and reduced side effects. In this review, we have summarized the studies of LSCs identification and therapeutic strategies with a commentary on recently developed cancer stem cell and LSCs targeting strategies by Nanomedicine.