Comparison of Salivary Alpha-Amylase, Sialic Acid, and pH in Pregnant and Nonpregnant Subjects

Q4 Dentistry

European Journal of General Dentistry Pub Date : 2021-01-01 DOI:10.1055/s-0041-1732771

M. Shirzaiy, Z. Dalirsani

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引用次数: 1

Abstract

Abstract Objectives During pregnancy, systemic physiological alterations lead to some changes in the oral cavity, which could prepare the mouth environment for oral and dental problems. This study was aimed to investigate salivary α-amylase, sialic acid levels, and pH levels in pregnant and nonpregnant females. Materials and Methods In this analytical, case–control study, unstimulated saliva samples were collected with spiting method from 35 pregnant women (case group) and 35 nonpregnant women (control group) and transferred to the laboratory to assess salivary α-amylase, sialic acid, and pH levels. Data were analyzed by SPSS (version: 19) software through statistical methods of independent t-test and analysis of variance. Results The mean sialic acid levels were 2.285 ± 1.230 mg/dL in pregnant and 2.744 ± 1.326 in nonpregnant women without any significant difference (p = 0.138). The mean salivary α-amylase concentrations were 2.461 ± 1.869 U/L and 2.439 ± 2.058 U/L, respectively, in pregnant and nonpregnant women, with no significant difference (p = 0.963). The mean salivary pH in nonpregnant women was significantly more than that in pregnant women (7.845 ± 0.430 and 6.868 ± 0.413, respectively) (p < 0.001). Also, the mean salivary pH levels in pregnant women were 7.474 ± 0.420 in the first trimester, 6.868 ± 0.413 in the second trimester, and 6.568 ± 0.387 in the third trimester, which were significantly different (p < 0.001). Conclusion Salivary sialic acid and α-amylase levels among pregnant women were no different from those of other subjects. During pregnancy, the salivary pH significantly reduced, and the mean salivary pH during pregnancy had a decreasing trend from the first trimester to the third trimester.

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孕妇和非孕妇唾液α -淀粉酶、唾液酸和pH值的比较

【摘要】目的孕期全身生理变化导致口腔发生一些变化，为口腔和牙齿问题的发生做好了口腔环境的准备。本研究旨在研究怀孕和未怀孕雌性唾液α-淀粉酶、唾液酸水平和pH水平。材料与方法在本分析性病例对照研究中，采用吐痰法采集35例孕妇(病例组)和35例非孕妇(对照组)的未刺激唾液样本，并将其送到实验室评估唾液α-淀粉酶、唾液酸和pH水平。数据分析采用SPSS (version: 19)软件，采用独立t检验和方差分析的统计方法。结果孕妇和非孕妇的唾液酸水平分别为2.285±1.230 mg/dL和2.744±1.326 mg/dL，差异无统计学意义(p = 0.138)。孕妇和非孕妇唾液α-淀粉酶平均浓度分别为2.461±1.869 U/L和2.439±2.058 U/L，差异无统计学意义(p = 0.963)。非妊娠妇女的平均唾液pH值(7.845±0.430)显著高于妊娠妇女(6.868±0.413)(p < 0.001)。妊娠前期、中期、晚期的唾液pH值分别为7.474±0.420、6.868±0.413和6.568±0.387，差异均有统计学意义(p < 0.001)。结论孕妇唾液中唾液酸和α-淀粉酶水平与其他人群无明显差异。妊娠期唾液pH值明显降低，妊娠期平均唾液pH值从妊娠早期到妊娠晚期呈下降趋势。

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来源期刊

European Journal of General Dentistry Dentistry-Dentistry (all)

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： European Journal of General Dentistry (EJGD) is one of the leading open-access international dental journal within the field of Dentistry. The aim of EJGD is publishing novel and high-quality research papers, as well as to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. EJGD publishes articles on all disciplines of dentistry including the cariology, orthodontics, oral surgery, preventive dentistry, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research.Moreover, EJGD also publish the scientific researches evaluating the use of new biomaterials, new drugs and new methods for treatment of patients with different kinds of oral and maxillofacial diseases or defects, the diagnosis of oral and maxillofacial diseases with new methods, etc. Moreover, researches on the quality of life, psychological interventions, improving disease treatment outcomes, the prevention, diagnosis and management of cancer therapeutic complications, rehabilitation, palliative and end of life care, and support teamwork for cancer care and oral health care for old patients are also welcome. EJGD publishes research articles, case reports, reviews and comparison studies evaluating materials and methods in the all fields of related to dentistry.