Nephron Sparing Surgery for Small Renal Mass at a University Teaching Hospital: A Six Years Retrospective Review

B. D. Rai, S. Poudyal, P. Dhital, M. Pradhan, S. Chapagain, B. Luitel, P. Chalise, U. Sharma, P. Gyawali
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Abstract

IntroductionNephron-sparing surgery (NSS) is the standard of care for clinical T1 (cT1), renal mass less than 7 cm, wheneverintervention is indicated. It has oncological outcome equivalent to radical nephrectomy in small renal massesand it also minimizes the progression to chronic kidney disease. However, there is paucity of data on outcomesof NSS in Nepalese population.MethodsA six years retrospective review of medical records of patients undergoing partial nephrectomy from Jan 2012 toDec 2017 in Department of Urology and Kidney Transplant Surgery at Tribhuvan University Teaching Hospital wasdone to determine its demographics and outcomes.ResultsTwenty eight patients underwent nephron sparing surgery for clinical T1 renal masses in the past six years.Complications occurred in three cases. Five of the lesions were benign and 23 malignant on final histology. Clearcell carcinoma was the commonest variant of renal cell cancer. Margin was positive in two cases and both werekept in close surveillance. There was no local recurrence and renal impairment during five to 60 months followup.ConclusionNephron sparing surgery is a safe procedure with good oncological outcome for clinical T1 renal mass. It preventsunnecessary nephrectomy in benign lesions as well as chronic renal impairment at the same time.KeywordsNephron sparing surgery, small renal mass
一所大学教学医院小肾脏肿块保留肾单位手术的六年回顾性研究
引言保留肾单位手术(NSS)是临床T1(cT1)的标准治疗方法,当需要任何干预时,肾质量小于7cm。它的肿瘤学结果相当于小肾块的根治性肾切除术,也最大限度地减少了慢性肾脏疾病的进展。然而,尼泊尔人口中NSS结果的数据很少。方法对2012年1月至2017年12月在特里布万大学教学医院泌尿外科和肾移植外科接受部分肾切除术的患者的医疗记录进行为期六年的回顾性审查,以确定其人口统计学和结果。结果在过去6年中,28例患者因临床T1肾肿块接受了保留肾单位的手术。3例出现并发症。在最终组织学检查中,5个病变为良性,23个为恶性。肾透明细胞癌是癌症最常见的变异。两例病例的Margin均为阳性,均处于密切监测状态。随访5至60个月,无局部复发和肾功能损害。结论保留肾单位手术是治疗临床T1肾肿块的一种安全、良好的肿瘤学方法,可预防良性病变和慢性肾功能损害的必要切除。关键词保留肾单位手术,小肾脏肿块
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