Conjunctival Seborrheic Keratosis Mimicking Ocular Surface Squamous Neoplasia

Abstract

Seborrheic keratosis is a benign epithelial neoplasia that commonly occurs on the face and eyelids of middle-aged individuals. Its occurrence on the conjunctiva is rare. We report a case of conjunctival seborrheic keratosis that clinically resembled an ocular surface squamous neoplasia (OSSN). A 77-year old male was referred with a right temporal juxta-limbal conjunctival mass. Based on its appearance, a clinical diagnosis of OSSN was made and a wide excisional biopsy, cryotherapy and amniotic membrane graft was performed. A diagnosis of seborrheic keratosis was confirmed by histopathology. Our case highlights the fact that conjunctival seborrheic keratosis, though rare, can mimic malignant lesions such as OSSN and should be considered in the differential diagnosis of conjunctival tumours.