Ethnomedicinal Uses, Antidiabetic, Antioxidant and Anti-inflammatory Activity of Gmelina arborea Roxb. and Its Bioactive Compounds: A Review

IF 0.4 Q4 CHEMISTRY, MULTIDISCIPLINARY
A. Attanayake, Ransika R Wadasinghe, P. Kalansuriya, B. M. R. Bandara
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引用次数: 0

Abstract

Gmelina arborea Roxb. (Family: Verbenaceae) is a medicinal plant that has been used in the treatment of diabetes mellitus (DM) since ancient times. Decoctions prepared from various parts of G. arborea are used in traditional systems of medicine as a remedy against DM and various other diseases. The present review describes the antidiabetic, antioxidant and anti-inflammatory properties of G. arborea extracts and their bioactive phytoconstituents that are likely to contribute to antidiabetic properties and their therapeutic importance in the management of diabetes. A comprehensive literature search was conducted using PubMed, ScienceDirect, Semantic Scholar and Google Scholar databases. Studies published from 1970 to 2021 were considered in this review. Out of the 157 results, 34 articles were excluded being duplications and 58 articles were excluded being outside the scope of this review. The remaining 65 articles were considered in this review. The in vitro and in vivo assays reveal the therapeutic potential of G. arborea in terms of antidiabetic, antioxidant and anti-inflammatory properties, indicating that the plant is a valuable source for developing non-toxic herbal formulations to manage DM.
木犀的民族医药、抗糖尿病、抗氧化和抗炎活性。及其生物活性化合物:综述
Gmelina arborea Roxb。马鞭草(马鞭草科)是一种药用植物,自古以来就被用于治疗糖尿病。在传统的医学体系中,从木参的不同部位制备的煎剂被用作治疗糖尿病和其他各种疾病的药物。本文综述了木参提取物的抗糖尿病、抗氧化和抗炎特性及其可能参与抗糖尿病特性的生物活性植物成分及其在糖尿病治疗中的重要作用。使用PubMed、ScienceDirect、Semantic Scholar和谷歌Scholar数据库进行全面的文献检索。本综述纳入了1970年至2021年发表的研究。在157个结果中,34篇文章被排除为重复,58篇文章被排除在本综述的范围之外。其余65篇文章纳入本综述。体外和体内实验结果显示,木参在抗糖尿病、抗氧化和抗炎方面具有治疗潜力,表明该植物是开发治疗糖尿病的无毒草药配方的宝贵来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Jordan Journal of Chemistry
Jordan Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
0.50
自引率
0.00%
发文量
7
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