Objective: To explore the clinical characteristics and diagnosis and treatment of phosphine poisoning in children, and further reduce the misdiagnosis, missed diagnosis rate, and mortality rate of the disease. Method: Three cases of phosphine poisoning misdiagnosed as fluoroacetamide poisoning admitted to the pediatric intensive care department of our hospital in 2018 were summarized and analyzed for their clinical characteristics, treatment status, and prognosis. The results showed that all 3 patients developed nausea and vomiting, with neurological and cardiovascular system damage being the main symptoms. They were misdiagnosed as fluoroacetamide poisoning. After detailed investigation of the medical history, it was diagnosed as phosphine poisoning. After treatment with blood purification, vitamin C, methylprednisolone, creatine phosphate, and necessary respiratory and circulatory support, 2 cases recovered and were discharged, while 1 case died clinically. Conclusion: Acute phosphine poisoning has a high mortality rate. For infants and young children, when parents provide a history of exposure to toxic substances such as aluminum phosphide or zinc phosphide or a suspected history of exposure, attention should be paid to whether phosphine poisoning has occurred, and blood purification treatment should be given as soon as possible to buy time for treating the child and improve prognosis.
期刊介绍:
Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.