Allergic bronchopulmonary aspergillosis in teenager with bronchial asthma

Revista Medica del Hospital General de Mexico Pub Date : 2018-07-01 DOI:10.1016/j.hgmx.2017.05.001

C.I. Urquiza-Ramírez, G.A. Eliosa-Alvarado, S. González-Flores, J.C. Fernández de Córdova-Aguirre, A.A. Velasco-Medina, G. Velázquez-Sámano

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引用次数: 2

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder caused by hypersensitivity mechanisms against antigens released by Aspergillus species, colonizing the airways.

We present the case of a 16-year-old male with a history of asthma and allergic rhinoconjunctivitis with a history of 15 months of cough with purulent sputum, intermittent fever and dyspnea. Thoracic tomography showed bronchiectasis accompanied by mucus impaction. He was treated with different antibiotics and steroid regimens, without a favorable clinical response. The presence of eosinophilia in the peripheral blood, immunoglobulin E Total, skin tests for Aspergillus positive guided the diagnosis of ABPA. Treatment with prednisone plus itraconazole was started, with remission of symptoms.

ABPA should be suspected in patients with asthma with poor response to treatment and alteration in radiologic studies. Treatment includes systemic steroids and avoiding exposure to Aspergillus.

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青少年支气管哮喘的变应性支气管肺曲菌病

过敏性支气管肺曲霉病(ABPA)是一种肺部疾病，由对曲霉物种释放的抗原的超敏机制引起，定殖在气道中。我们提出的情况下，一个16岁的男性哮喘和过敏性鼻结膜炎的历史，15个月的咳嗽化脓痰，间歇性发烧和呼吸困难的历史。胸部断层扫描显示支气管扩张伴黏液嵌塞。他接受了不同的抗生素和类固醇治疗方案，但没有良好的临床反应。外周血嗜酸性粒细胞增多、免疫球蛋白E总值、皮肤试验曲霉菌阳性指导ABPA的诊断。开始强的松加伊曲康唑治疗，症状缓解。对治疗反应差和放射学检查改变的哮喘患者应怀疑ABPA。治疗包括全身类固醇和避免接触曲霉。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Medica del Hospital General de Mexico

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The Medical Journal of the Hospital General de Mexico is the official organ of the Medical Society of the Hospital General de Mexico. The journal accepts articles in Spanish or in English on the field of hospital medicine. The journal publishes original articles, clinical cases, reviews articles, history notes, issues on medical education, short communications and editorials at the invitation of the Society. All articles are double blind peer reviewed by at least 2 reviewers and finally classified as accepted or rejected by the Editorial Board.