Postirradiation Angiosarcoma – A Late, Severe Complication of Radiotherapy for Mammary Neoplasm

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL
Raluca Lascu, A. Alexandru, Alexandra Oltenescu, Oana Vlaicu, R. Andrei
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引用次数: 0

Abstract

"Angiosarcoma is a malignant tumor derived from the endothelium of the blood and lymphatic vessels. Its aggressive behavior results in a poor prognosis for the patients. Radiation-associated angiosarcoma is a rare recently described particular subtype of angiosarcoma best shown in patients after treatment of breast cancer. The latency period of development is approximately 8 years, thus the 5-year standard follow-up after mammary neoplasm therapy needs to be extended up to 10 years. Radiotherapy is an independent risk factor for angiosarcoma development. Rapid diagnosis is essential for prompt therapeutical intervention to improve the patient’s prognosis. The importance of early diagnosis is emphasized by a case of a 54 years old woman, with a diagnosis of breast cancer treated by sectorectomy and radiotherapy 7 years prior, presenting to our Dermatology Department for the recent occurence of erythemato-violaceous cutaneous patches on the area subjected to radiotherapy. "
放射后血管肉瘤——乳腺肿瘤放射治疗的晚期严重并发症
血管肉瘤是一种源自血管内皮和淋巴管的恶性肿瘤。其攻击性行为导致患者预后不良。辐射相关性血管肉瘤是最近发现的一种罕见的特殊亚型血管肉瘤,最见于乳腺癌治疗后的患者。发展潜伏期约为8年,因此乳腺肿瘤治疗后5年的标准随访需要延长至10年。放疗是血管肉瘤发展的独立危险因素。快速诊断是必要的及时治疗干预,以改善患者的预后。早期诊断的重要性是通过一个54岁的女性病例来强调的,她被诊断为乳腺癌,7年前接受了部门切除术和放疗,最近在接受放疗的区域出现红斑-紫色皮肤斑块,到我们的皮肤科就诊。”
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来源期刊
Romanian Journal of Military Medicine
Romanian Journal of Military Medicine MEDICINE, GENERAL & INTERNAL-
自引率
33.30%
发文量
2
审稿时长
12 weeks
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