Value of multiparameter quantitative CT in evaluating the prognosis of COVID-19

Q4 Medicine
Yuannan Hu, Deng Ming, Hu Jinxiang, Zai-peng Zhang, Xue Guobin, Liejun Mei, Haibo Xu
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Abstract

Objective: To investigate the value of multi-parameter quantitative CT combining with HRCT in evaluating the prognosis of coronavirus disease 2019 (COVID-19) Methods: Sixty-nine cases were included in this retrospective study All of the cases were primarily diagnosed with common type of COVID-19 when admitted to hospital According to the clinical prognosis and the changes of image appearance, three groups were divided Group A with decreasing extent of lesions (21 cases) and group B with increasing extent of lesions (25 cases) were both common type of COVID-19 without converting into severe type Group C (23 cases) converted common type into severe type during hospitalization Multiple CT parameters among the groups were compared Results: The changes of the multiple parameters of CT after treatment, such as the total volume of lesions, GGO volume, and the volume of the consolidation and MLA, had a significant difference among the three groups When the cut-off values for the increasing total volume, GGO volume, consolidation volume, and MLA were determined to be 231 46 cm3, 168 58 cm3, 74 46 cm3, and 57 Hu, the sensitivity (95 7%, 82 6%, 73 9%, and 78 3%) and specificity (91 3%, 91 3%, 93 5%, and 87%) of the diagnosis of common type converting into severe type were optimal and the areas under ROC curve were 0 961, 0 914, 0 885, and 0 885 Conclusion: The changes of the volumes of total lesions, GGO and consolidation and the change of MLA between follow-up CT and first CT are important prognostic factors in patients with COVID-19 Common type COVID-19 patients with total volume of lesions increasing >231 46 cm3, GGO volume increasing >168 58 cm3, consolidation volume increasing >74 46 cm3, or MLA increasing >57 Hu are more likely to convert into severe type The multiparameter quantitative CT combined with HRCT has an effect on evaluating the prognosis of COVID-19 © 2021, Editorial Board of Medical Journal of Wuhan University All right reserved
多参数定量CT评价新冠肺炎预后的价值
目的:探讨多参数定量CT联合HRCT评价冠状病毒病2019 (COVID-19)预后的价值。本回顾性研究纳入69例病例,所有病例入院时均根据临床预后及影像学改变初步诊断为普通型COVID-19。3组分为病变程度减小组(21例)和病变程度增大组(25例),均为普通型,未转化为重症;C组(23例)住院期间转化为普通型;治疗后CT的多个参数的变化,如病变的总量,GGO体积,和整合的体积和MLA,三组中有显著差异时,截止值增加总量,GGO体积,体积,整合和MLA决心46 231立方厘米,168 58立方厘米,74年46立方厘米,57胡,灵敏度(95年7%,82年6%,73年9%,78年3%)和特异性(91年3%,91年3%,93年5%,普通型转化为重症的诊断最优(87%),ROC曲线下面积分别为0.961、0.914、0.885、0.885。总病灶体积、GGO体积和实变体积的变化以及随访CT与首次CT间MLA的变化是影响COVID-19患者预后的重要因素。普通型COVID-19患者病灶体积增大>231 46 cm3, GGO体积增大>168 58 cm3,实变体积增大>74 46 cm3,多参数定量CT联合HRCT评估COVID-19预后©2021,武汉大学医学杂志编辑委员会版权所有
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来源期刊
武汉大学学报(医学版)
武汉大学学报(医学版) Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
7289
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