Efficacy of negative pressure suction and external testosterone cream in the treatment of small penis after hypospadias surgery

Q4 Medicine

中华实用儿科临床杂志 Pub Date : 2020-03-23 DOI:10.3760/CMA.J.CN101070-20190222-00124

Liang Zhao, Cuiping Song, Haiyang Zhang, Hui Liu, Wang Rao, Xusheng Tian, Dan-chen Su, Xinhui Sun

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引用次数: 0

Abstract

Objective To explore the effective method for treatment of small and short penis after hypospadias surgery. Method s From November 2017 to November 2018, 57 children aged 4 to 14[mean age(7.91±2.89)years] with hypospadias who met the diagnostic criteria of small penis were reexamined at the First Affiliated Hospital of Xin-xiang Medical University.They were randomly divided into the physical treatment group and the drug treatment group according to the order of visits, and the untreated patients were included in the control group.Among them, 21 patients in the physical treatment group were treated with penile rehabilitation therapy apparatus, supplemented by Salvia mil-tiorrhiza bath (30 minutes/time, once/day, 10 days), and 20 patients in the drug treatment group were treated with Testosterone cream topically (3 times/day, 10 days). Penile relaxation length, stretch length, transverse and longitudinal diameters of glans in 2 groups before and after the treatment were measured.The relevant indexes of 16 patients in the control group measured before and after 10 days and compared with those in the treatment group. Result s (1)The penile relaxation length in the physical treatment group increased from (25.48±6.13) mm to (30.72±6.49) mm, the length of stretch increased from (34.90±7.71) mm to (41.08±8.43) mm, the transverse diameter of glans increased from (14.81±3.40) mm to (16.57±3.42) mm, and the longitudinal diameter increased from (13.94±3.15) mm to (15.82±3.52) mm, and the differences were statistically significant (all P 0.05). (4) Compared with the control group, the penile relaxation length, the length of stretch, transverse diameter and longitudinal diameters of glans in the physical treatment group increased significantly, and the differences of growth values between the two groups were statistically significant (all P<0.05). (5) Compared with the control group, the penile relaxation length, the length of stretch, transverse diameter and longitudinal diameters of glans in the drug treatment group also increased significantly, and the difference of growth values between the two groups were statistically significant (all P<0.05). (6) The growth of penile relaxation length, the length of stretch and transverse and longitudinal diameters in the drug treatment group were higher than those in the physical treatment group, and the difference of growth values were statistically significant (all P<0.05). Conclusions Both the negative pressure suction method and topical application of Testosterone cream are effective in the treatment of small and short penis after hypospadias surgery.However, Testosterone cream is difficult to obtain, and the treatment of negative pressure suction is simple, noninvasive, painless and free of adverse reactions. Key words: Hypospadias; Small penis; Treatment; Negative pressure suction; Testosterone cream

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负压吸引联合外用睾酮乳膏治疗尿道下裂术后小阴茎的疗效观察

目的探讨尿道下裂术后阴茎短小的有效治疗方法。方法2017年11月至2018年11月，在新乡医科大学第一附属医院对57例4～14岁（平均年龄（7.91±2.89）岁）符合小阴茎诊断标准的尿道下裂患儿进行复查，按就诊顺序随机分为物理治疗组和药物治疗组，将未经治疗的患者纳入对照组。其中，物理治疗组21例采用阴茎康复治疗仪治疗，辅以丹参浴（30分钟/次，1次/天，10天），药物治疗组20例采用睾酮乳膏局部治疗（3次/天、10天）。测量两组患者治疗前后阴茎松弛长度、伸缩长度、龟头横径和纵径。对照组16例患者在10天前和10天后测量相关指标，并与治疗组进行比较。结果s（1）物理治疗组阴茎松弛长度由（25.48±6.13）mm增加到（30.72±6.49）mm，伸展长度由（34.90±7.71）mm增加至（41.08±8.43）mm，龟头横径由（14.81±3.40）mm增加为（16.57±3.42）mm，纵径由（13.94±3.15）mm增加（15.82±3.52）mm，差异有统计学意义（均P＜0.05）。（4）物理治疗组阴茎松弛长度、伸缩长度、龟头横径和纵径均较对照组显著增加，两组生长值差异有统计学意义（均P<0.05）。（5）与对照组相比，药物治疗组阴茎松弛长度、伸长度、龟头横径和纵径也显著增加，两组生长值差异有统计学意义（均P<0.05）。（6）药物治疗组阴茎松弛长度、拉伸长度、横径和纵径的生长均高于物理治疗组，结论负压吸引法和局部应用睾酮乳膏治疗尿道下裂术后阴茎小而短是有效的。然而，睾酮乳膏很难获得，负压吸引治疗简单、无创、无痛且无不良反应。关键词：尿道下裂；小阴茎；治疗；负压吸入；睾酮乳膏

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来源期刊

中华实用儿科临床杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

14243

期刊介绍： Chinese Journal of Applied Clinical Pediatrics ( semi-monthly ) is a core journal of paediatrics under the supervision of China Association for Science and Technology, sponsored by Chinese Medical Association and undertaken by Xinxiang Medical College. Founded in 1986, it is openly circulated both at home and abroad. The journal has several columns, such as Expert Forum, Experimental Research and Paediatric Surgery, which are mainly for paediatric medical workers and medical researchers in hospitals. Its purpose is to reflect the new theories and technologies in paediatric medicine and scientific research at home and abroad, and to promote academic exchanges. Chinese Journal of Applied Clinical Pediatrics is a source journal of China Science Citation Database (CSCD), a core journal of Peking University, a source journal of Chinese science and technology paper statistics (China Science and Technology Core Journals), a core academic journal of RCCSE, a high-quality scientific and technical journal of China, a high-quality scientific and technical journal of China Association for Science and Technology, and a high-quality scientific and technical journal of China Biomedical Science and Technology Association. We have been published in China Biomedical Literature Database (SinoMed), China Knowledge Network, Wanfang Data Knowledge Service Platform, China Academic Journal Abstracts, Scopus Database, Chemical Abstracts (USA), Japan Science and Technology Agency (JSTA) Database, Copernicus Abstracts (Poland), Abstracts of the Centre for Agricultural and Biological Sciences (CABS) of the United Kingdom, Cambridge Scientific Abstracts ProQuest Database, WHO Medical Journal of the Western Pacific Region (WMPR), and WHO Medical Journal of the Western Pacific Region (WMPR) of the United States. We have been included in dozens of authoritative databases at home and abroad, such as WHO Western Pacific Region Index of Medicine (WPRIM), Ullrich's Guide to Periodicals, and so on.