Evaluation of Health Related Quality of Life in Dogs Treated with Chemotherapy for Lymphoma

IF 0.7 4区农林科学 Q3 VETERINARY SCIENCES

Acta Veterinaria-Beograd Pub Date : 2023-06-01 DOI:10.2478/acve-2023-0017

Elena Atanaskova Petrov, Miroslav Kjosevski, I. Celeska

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Abstract

Abstract Lymphoma is the most common hematopoietic tumor in dogs. The standard diagnostic approach and staging includes detailed clinical history, physical examination and extended laboratory workup including lymph node cytology. Multidrug chemotherapy is the main treatment of the disease. Often, owners are concerned about the side effects of the treatment and the quality of life of their dog during chemotherapy. The aim of this study was to analyze the health related wellbeing of the patients with lymphoma previous, during and at the end of the chemotherapy. Five patients with multicentric lymphoma were monitored in three phases (beginning, middle and end of chemotherapy). The monitoring included clinical examination, laboratory analyses and a questionnaire for the owner. Results revealed significant improvement (p< 0.1) of the basic red blood cells parameters (RBC, PCV and Hb), platelets (PLT) as well as liver enzymes (ALT, AST) and protein status (total protein and globulin). Regarding the life quality assessed by the owners, dogs' appetite, general health compared to each visit and the current quality of life were significantly improved (p<0.1) and all of the owners were satisfied with the decision for chemotherapy.

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淋巴瘤化疗犬的健康相关生活质量评价

摘要淋巴瘤是狗最常见的造血肿瘤。标准的诊断方法和分期包括详细的临床病史、身体检查和包括淋巴结细胞学在内的广泛实验室检查。多种药物化疗是该病的主要治疗方法。通常，主人会担心治疗的副作用和化疗期间狗的生活质量。本研究的目的是分析淋巴瘤患者在化疗前、化疗中和化疗结束时的健康状况。对5例多中心淋巴瘤患者分三个阶段（化疗开始、中期和结束）进行监测。监测包括临床检查、实验室分析和业主问卷调查。结果显示，基本红细胞参数（RBC、PCV和Hb）、血小板（PLT）、肝酶（ALT、AST）和蛋白质状态（总蛋白和球蛋白）均有显著改善（p<0.01）。关于主人评估的生活质量，与每次访问相比，狗的食欲、总体健康状况以及目前的生活质量都有了显著改善（p<0.01），所有主人都对化疗的决定感到满意。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Veterinaria-Beograd 农林科学-兽医学

CiteScore

1.30

自引率

16.70%

发文量

审稿时长

18-36 weeks

期刊介绍： The Acta Veterinaria is an open access, peer-reviewed scientific journal of the Faculty of Veterinary Medicine, University of Belgrade, Serbia, dedicated to the publication of original research articles, invited review articles, and to limited extent methodology articles and case reports. The journal considers articles on all aspects of veterinary science and medicine, including the diagnosis, prevention and treatment of medical conditions of domestic, companion, farm and wild animals, as well as the biomedical processes that underlie their health.