EFEK PENAMBAHAN TERAPI PULSED ULTRASOUND (US) LOW INTENSITY PADA LATIHAN KINESIOTHERAPY TERHADAP GAMBARAN C-REACTIVE PROTEIN (CRP) PADA KASUS OSTEOARTHRITIS (OA) GENU DI RSUD dr. DRADJAT PRAWIRANEGARA KABUPATEN SERANG

Abstract

Background: The advancement of knowledge about molecular biology in the 90s changed the paradigm regarding the pathogenesis of Osteoarthritis (OA) genu which caused multifactorial causes, begining with the emergence of inflammatory mediators and not merely degenerative processes. Purpose: To Analyze the differences in CRP description in OA genu patients after receiving additional low intensity pulsed Ultrasound (US) therapy in kinesiotherapy exercise compared to after receiving kinesiotherapy exercise. Method: This study is true experimental, using the pretest-posttest control group design. The number of respondents was 26 patients who had been diagnosed with OA genu who came to the Physiotherapy clinic at RSUD dr. Dradjat Prawiranegara Serang District which is adjusted to the inclusion criteria. Respondents were divided into two groups selected by random alocation. The first group consisted of 13 people given the kinesiotherapy exercise and referred to the control group. The second group consisted of 13 people given an addition of low intensity pulsed Ultrasound (US) therapy in kinesiotherapy exercise and referred to the treatment group. CRP examination uses the immunoturbidimetry method of blood plasma with heparin anticoagulation. Result: (1) there was a significant difference in the CRP description in OA genu patients after receiving the kinesiotherapy exercise (control group) average from 0.35±0.28 mg/dL to be 0.19±0.15 mg/dL with a value of p<0.05; (2) there was a significant difference in the CRP description in OA genu patients after receiving an addition of low intensity pulsed Ultrasound (US) therapy in kinesiotherapy exercise (treatment group) average from 0.75±0.53 mg/dL to be 0.44±0.33 mg/dL with a value of p<0.05; (3) there was difference CRP description in OA genu patients between those who received an addition of low intensity pulsed Ultrasound (US) therapy in kinesiotherapy exercise those who received a kinesiotherapy exercise with a value of p<0.05.