Ectopic Sebaceous Glands over Buccal Mucosa: A Case Report on Fordyce Spot

Abstract

objective: To highlight the importance of histopathological diagnosis to identify Fordyce spots. Background: These are normal variants in which sebaceous glands are ectopically located over the mucosal surfaces and are not in association with hair follicles. Fordyce spots, or Fordyce granules, can be found on the genital mucosa (glans penis and labia minor), esophagus, gastroesophageal junction, uterine cervix, sole of the foot, thymus, and tongue. Case description: The following two cases are included in our case report: Conclusion: Histopathology is the gold standard of diagnosis in this condition; it is imperative for the pathologist to identify the presence of Fordyce spots. Clinical significance: Fordyce spots over the oral mucosa are reported rarely and is known to have an array of clinical mimics such as malignancies of oral mucosa.