The 5-Item Modified Frailty Index for Risk Stratification of Patients Undergoing Total Elbow Arthroplasty.

The Hand Pub Date : 2023-11-01 Epub Date: 2022-06-11 DOI:10.1177/15589447221093728
Adam M Gordon, Charles A Conway, Bhavya K Sheth, Matthew L Magruder, Jack Choueka
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Abstract

Background: Frailty, quantified using the 5-item modified frailty index (mFI-5), has been shown to predict adverse outcomes in orthopaedic surgery. The utility in total elbow arthroplasty (TEA) patients is unclear. We evaluated if increasing frailty would correlate with worse postoperative outcomes.

Methods: A retrospective assessment of patients in the American College of Surgeons National Surgery Quality Improvement Program undergoing primary TEA was performed. The mFI-5 was calculated by assigning 1 point for each comorbidity (diabetes, hypertension, congestive heart failure, chronic obstructive pulmonary disease, and functionally dependent health status). Poisson regression was used to evaluate mFI-5 scores on complications, length of stay (LOS), and adverse discharge. A significance threshold was at P < .05.

Results: In total, 609 patients were included; 34.5% (n = 210) were not frail (mFI = 0), 44.0% (n = 268) were slightly frail (mFI = 1), and 21.5% (n = 131) were frail (mFI ≥ 2). As mFI score increased from 0 to ≥ 2, the following rates increased: any complication (9.0%-19.8%), major complication (11.0%-20.6%), cardiac complication (0.0%-2.3%), hematologic complication (3.3%-9.2%), adverse discharge (2.9%-22.9%), and LOS from 2.08 to 3.97 days (all P < .048). Following adjustment, Poisson regression demonstrated patients with a mFI ≥ 2 had increased risk of major complication (risk ratio [RR]: 2.13; P = .029), any complication (RR: 2.49; P = .032), Clavien-Dindo IV complication (RR: 5.53; P = .041), and adverse discharge (RR: 5.72; P < .001).

Conclusions: Frailty is not only associated with longer hospitalizations, but more major complications and non-home discharge. The mFI-5 is a useful risk stratification that may assist in decision-making for TEA.

全肘关节置换术患者危险分层的5项修正脆性指数。
背景:虚弱,用5项修正的虚弱指数(mFI-5)量化,已被证明可以预测骨科手术的不良结果。在全肘关节置换术(TEA)患者中的应用尚不清楚。我们评估了虚弱的增加是否与较差的术后结果相关。方法对美国外科医师学会国家手术质量改进计划中接受初级TEA的患者进行回顾性评估。mFI-5的计算方法是为每一种合并症(糖尿病、高血压、充血性心力衰竭、慢性阻塞性肺疾病和功能依赖健康状况)赋1分。采用泊松回归评价mFI-5评分对并发症、住院时间(LOS)和不良出院的影响。显著性阈值为P < 0.05。结果共纳入609例患者;34.5% (n = 210)为不虚弱(mFI = 0), 44.0% (n = 268)为轻度虚弱(mFI = 1), 21.5% (n = 131)为虚弱(mFI≥2)。随着mFI评分从0到≥2的增加,任何并发症(9.0% ~ 19.8%)、主要并发症(11.0% ~ 20.6%)、心脏并发症(0.0% ~ 2.3%)、血液学并发症(3.3% ~ 9.2%)、不良排出(2.9% ~ 22.9%)和LOS (2.08 ~ 3.97 d)的发生率增加(P均< 0.048)。调整后泊松回归显示mFI≥2的患者主要并发症的风险增加(风险比[RR]: 2.13;P = 0.029),任何并发症(RR: 2.49;P = 0.032), Clavien-Dindo IV并发症(RR: 5.53;P = 0.041),不良排出(RR: 5.72;P < 0.001)。结论虚弱不仅与住院时间延长有关,而且与主要并发症和非居家出院有关。mFI-5是一个有用的风险分层,可能有助于TEA的决策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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