Forecasting the “T” Stage of Esophageal Cancer by Deep Learning Methods: A Pilot Study

S. Çelik, Serpil Deniz, Ali Mahir Gündüz, Leyla Turgut Çoban, Zehra İlik Akman, A. Sohail, Serhat Güneş, Barzin Tajani, M. Ç. Kotan
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Abstract

Research motivation: Staging esophageal cancer is of paramount importance for treatment. With conventional methods, accuracy of staging is low, we aimed to improve the accuracy of the “T” stage of esophageal cancer by using deep learning techniques. Method/Material: Clinically diagnosed esophageal cancer patients were prospectively observed and their data were collected. jpeg images were collected from the Computed Tomography of patients. 80% of the data were used for training and 20% for tests. Pathology results were used as the gold standard in the training of deep learning algorithms. EfficientNetB7 and ResNet152V2 models were used in the study. Both architectures with convolutional neural networks have Convolutional layers, pool layers, and fully connected layers. Results: A total of 477 images of 50 patients were analyzed. EfficientNetB7 makes predictions with a total of 64,107,931 parameters, and ResNet152V2 58,339,844 parameters within seconds (2[Formula: see text]s) at rates close to the accuracy offered by humans. With the EfficientNetB7 architecture, one of the Convolutional Neural Networks used in this study, 90% accuracy was achieved in the “T” staging of esophageal cancer. Conclusion: Despite the very limited dataset, deep learning algorithms can perform effective and reliable staging under the supervision of an experienced radiologist. With more datasets, the precision of the estimation can increase.
用深度学习方法预测食管癌“T”期的初步研究
研究动机:食管癌的分期对治疗至关重要。传统方法对食管癌分期准确率较低,我们旨在利用深度学习技术提高食管癌“T”期的准确率。方法/材料:对临床诊断的食管癌患者进行前瞻性观察并收集资料。从患者的计算机断层扫描中收集jpeg图像。80%的数据用于训练,20%用于测试。病理结果被用作深度学习算法训练的金标准。采用高效netb7和ResNet152V2模型。卷积神经网络的两种架构都有卷积层、池层和全连接层。结果:共分析50例患者的477张图像。EfficientNetB7在数秒内预测了总共64,107,931个参数,而ResNet152V2在数秒内预测了58,339,844个参数(2[公式:见文本]),其准确率接近人类提供的准确率。使用本研究中使用的卷积神经网络之一的effentnetb7架构,食管癌的“T”分期准确率达到90%。结论:尽管数据集非常有限,但深度学习算法可以在经验丰富的放射科医生的监督下进行有效可靠的分期。随着数据集的增加,估计的精度可以提高。
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