Insights into the inhibitory mechanism and molecular interaction of novel alkaloids from Beilschmiedia glabra with lipoxygenase and acetylcholinesterase

IF 2.4 Q3 Computer Science

Journal of Theoretical & Computational Chemistry Pub Date : 2019-12-01 DOI:10.1142/s021963361950038x

Wan Mohd Nuzul Hakimi Wan Salleh, T. H. Ogunwa

引用次数: 0

Abstract

In this study, the mechanism underlying acetylcholinesterase (AChE) and 5-lipoxygenase (LOX) inhibition by two novel alkaloids, beilschglabrine A and beilschglabrine B, as well as their interaction...

查看原文本刊更多论文

新生物碱对脂氧合酶和乙酰胆碱酯酶的抑制机制及分子相互作用的研究

在本研究中，研究了两种新型生物碱beilschglabrine A和beilschglabrine B抑制乙酰胆碱酯酶(AChE)和5-脂氧合酶(LOX)的机制及其相互作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Theoretical & Computational Chemistry 化学-化学综合

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： The Journal of Theoretical and Computational Chemistry (JTCC) is an international interdisciplinary journal aimed at providing comprehensive coverage on the latest developments and applications of research in the ever-expanding field of theoretical and computational chemistry. JTCC publishes regular articles and reviews on new methodology, software, web server and database developments. The applications of existing theoretical and computational methods which produce significant new insights into important problems are also welcomed. Papers reporting joint computational and experimental investigations are encouraged. The journal will not consider manuscripts reporting straightforward calculations of the properties of molecules with existing software packages without addressing a significant scientific problem. Areas covered by the journal include molecular dynamics, computer-aided molecular design, modeling effects of mutation on stability and dynamics of macromolecules, quantum mechanics, statistical mechanics and other related topics.