The Effect of the Number of Fields on Radiotherapy Plans of Breast Cancer Patients in Three-Dimensionally Conformal Radiotherapy Plans: Dosimetric Studies

IF 0.4 Q4 ONCOLOGY
Zezy Mansour Bazeed, E. Attalla, I. Awad, M. Hamid, A. Sarhan
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引用次数: 1

Abstract

Background: The objective of this study was to compare the dosimetric outcome of plans with more fields to those with fewer ones for breast cancer patients. Method: Twenty-three breast cancer patients were examined in this experimental study. Two groups of these patients were planned by treatment planning system. The number of beams was changed for each group, and the dosimetric parameters were calculated. The dose volume histogram (DVH) and the statistical analyses were performed for the two plans of all patients. Results: The DVH for the planning target volume (PTV) of the two techniques was estimated. Optimized plans were carried out to ensure that 95 % of the target volume takes 95 % of the dose. Based on the statistical analysis, the best coverage of dose had no relationship with the number of beams because the P-value of V105 %, V95 %,V110 %, D mean, D max, CI, HI, and D5% were 0.9537, 0.9152, 0.3446, 0.8156, 0.9516, 0.7888, 0.2127, and 0.7282, respectively. The Mean ±SEM for all PTV parameters was nearly the same. Also, the organ at risk had no significant difference after changing the number of beams, which means that the complication to normal tissue was nearly the same for both plans. Conclusion: The number of beams has no effect on PTV and normal tissue. Therefore, it is important for medical physicists to conduct the optimized plan without exceeding the number of beams to reduce the scattered radiation.
三维适形放疗计划中场数对乳腺癌患者放疗计划的影响:剂量学研究
背景:本研究的目的是比较具有较多磁场的方案与较少磁场的方案对乳腺癌患者的剂量学结果。方法:对23例乳腺癌患者进行实验研究。采用治疗计划系统对两组患者进行治疗计划。改变每组的光束数,并计算剂量学参数。对所有患者进行剂量-体积直方图(DVH)和统计分析。结果:估计了两种技术的规划靶体积(PTV)的DVH。优化方案,以确保95%的目标体积采取95%的剂量。经统计分析,v105%、v95%、v110%、D mean、D max、CI、HI、D5%的p值分别为0.9537、0.9152、0.3446、0.8156、0.9516、0.7888、0.2127、0.7282,最佳剂量覆盖率与束数无关。所有PTV参数的平均值±SEM几乎相同。此外,在改变光束数量后,处于危险中的器官没有显着差异,这意味着两种方案对正常组织的并发症几乎相同。结论:束数对PTV及正常组织无影响。因此,在不超过光束数的情况下进行优化方案以减少散射辐射对医学物理学家来说是非常重要的。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: Middle East Journal of Cancer (MEJC) is an international peer-reviewed journal which aims to publish high-quality basic science and clinical research in the field of cancer. This journal will also reflect the current status of research as well as diagnostic and treatment practices in the field of cancer in the Middle East, where cancer is becoming a growing health problem. Lastly, MEJC would like to become a model for regional journals with an international outlook. Accordingly, manuscripts from authors anywhere in the world will be considered for publication. MEJC will be published on a quarterly basis.
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