Karakteristik Mikroemulsi a-Tokoferol pada Perbandingan Campuran Tiga Surfaktan Nonionik dan Lama Pengadukan

IF 0.2 2区艺术学 0 MUSIC

Journal of the Royal Musical Association Pub Date : 2021-03-26 DOI:10.24843/JRMA.2021.V09.I01.P04

Putu Ayu Sucitawati, Lutfi Suhendra, G. G. Putra

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引用次数: 0

Abstract

Microemulsions have thermodynamics and stable kinetics as carriers of ?-tocopherol compounds. This study aimed to know the effect of mixtures ratio of three nonionic surfactants and stiring time on the characteristics of ?-tocopherol microemulsion, as well as to obtain the best stiring time and mixture ratio of three nonionic surfactants to produce ?-tocopherol microemulsion. This experiment used a randomized block design with two factors. The first factor is the ratio of a mixture of three nonionic surfactants with Hydrophilic-Lipophilic Balance (HLB) 14.5. The second factor is stirring time. Data were analyzed using analysis of variance and continued with BNJ test. Test the effectiveness index to determine the best treatment. The results showed that the comparison of three surfactant mixtures, stirring duration and interaction between treatments significantly affected the characteristics of ?-tocopherol microemulsion. Comparison of the mixture of three surfactants Tween 80: Span 80: Tween 20 (v / v%) HLB 14.5 consisting of F2 (89,5 : 5,5 : 5) and 4 minutes stirring time is the best treatment for the characteristics of ?-Tocopherol microemulsion. The best treatment has the characteristics of ?-tocopherol microemulsions namely transparent appearance, stable to centrifugation (4500 rpm), pH (4.5; 5.5 and 6.5) and dilution (1: 9, 1:49 and 1:99) with Turbidity index values ??are below 1 percent. Microemulsion turbidity index values ??before and after centrifugation were 0.19 percent and microemulsion turbidity at pH 4.5 and 1: 9 dilution were 0.11 percent. Keywords: microemulsion, stirring time, surfactan non ionic, ?-Tocoferol

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微乳酸a-Tokoferol的特征是三次非离子代孕和长期混合

微乳作为-生育酚类化合物的载体，具有良好的热力学和稳定的动力学。本研究旨在了解三种非离子表面活性剂的混合比例和搅拌时间对-生育酚微乳液特性的影响，并获得制备-生育酚微乳液的最佳搅拌时间和三种非离子表面活性剂的混合比例。本试验采用双因素随机区组设计。第一个因素是三种非离子表面活性剂的混合物的亲水性-亲脂性平衡(HLB)为14.5的比例。第二个因素是搅拌时间。数据分析采用方差分析，继续采用BNJ检验。检测疗效指标，确定最佳治疗方案。结果表明，三种表面活性剂配比的比较、搅拌时间和处理间的相互作用对-生育酚微乳的特性有显著影响。比较三种表面活性剂Tween 80: Span 80: Tween 20 (v / v%) HLB 14.5组成的F2(89,5:5, 5:5)和4 min搅拌时间是对?-生育酚微乳液特性的最佳处理。最佳处理具有-生育酚微乳的特点，即外观透明，离心稳定(4500转/分)，pH (4.5;5.5和6.5)和稀释度(1:9,1:49和1:99)，浊度指数值为??都低于1%。微乳浊度指数值??离心前后的浊度为0.19%，pH为4.5和1:9稀释时的微乳浊度为0.11%。关键词:微乳液，搅拌时间，非离子型表面活性剂，-生育醇

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来源期刊

Journal of the Royal Musical Association MUSIC-

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0.50

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0.00%

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期刊介绍： The Journal of the Royal Musical Association was established in 1986 (replacing the Association"s Proceedings) and is now one of the major international refereed journals in its field. Its editorial policy is to publish outstanding articles in fields ranging from historical and critical musicology to theory and analysis, ethnomusicology, and popular music studies. The journal works to disseminate knowledge across the discipline and communicate specialist perspectives to a broad readership, while maintaining the highest scholarly standards.