Antioxidative and Circadian Rhythm Regulation Effect of Quercus gilva Extract

Q2 Engineering

Journal of the Korean wood science and technology Pub Date : 2022-09-01 DOI:10.5658/wood.2022.50.5.338

Jin-Sung Huh, Sora Lee, Dong-Soo Kim, M. Choi, Hyunmo Choi, Kyung-Ha Lee

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引用次数: 2

Abstract

Herein, water and ethanol extracts were obtained from the leaves, branches, kernels, and pericarp of Quercus gilva and subsequently analyzed for antioxidant activity and circadian rhythm regulation effects. Candidate components that may affect circadian rhythm and antioxidant activity were investigated to discover potential functional materials. Antioxidant activity was analyzed via 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity assays, showing that the hot water extract exhibited higher activity than that of the ethanol extract. In particular, the branch extract showed high antioxidant activity. By measuring total contents of polyphenols, flavonoids, and tannins, the hot water branch extract showed the highest concentrations, highlighting their significant contribution to the antioxidant activity. Examination of the circadian rhythm regulation of each extract showed that the ethanol extract exhibited greater impacts on the circadian rhythm amplitude compared to the water extract. The branch ethanol extract induced circadian rhythm amplitude changes via clock gene Bmal1 expression regulation. Determination of 12 phenolic compound concentrations showed that the branch ethanol extract contained many phenolic compounds, including catechin. This suggests that these compounds affected circadian rhythm regulation. In conclusion, the hot water branch extract has potential as an natural antioxidant material, while the corresponding ethanol extract has potential as a functional material for regulating circadian rhythm.

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栎树提取物的抗氧化及昼夜节律调节作用

本研究从栎树的叶、枝、仁和果皮中提取水和乙醇提取物，分析其抗氧化活性和昼夜节律调节作用。研究了可能影响昼夜节律和抗氧化活性的候选成分，以发现潜在的功能材料。通过2,2-二苯基-1-吡啶肼(DPPH)和2,2 ' -氮基-双(3-乙基苯并噻唑-6-磺酸)(ABTS)自由基清除实验分析了其抗氧化活性，结果表明热水提取物比乙醇提取物具有更高的抗氧化活性。其中，分枝提取物具有较高的抗氧化活性。通过对多酚类、黄酮类和单宁类总含量的测定，热水支提物的含量最高，显示出其对抗氧化活性的显著贡献。对每种提取物的昼夜节律调节的检查表明，与水提取物相比，乙醇提取物对昼夜节律幅度的影响更大。树枝乙醇提取物通过调节生物钟基因Bmal1的表达诱导昼夜节律振幅的变化。对12种酚类化合物的浓度测定表明，枝乙醇提取物中含有多种酚类化合物，其中包括儿茶素。这表明这些化合物影响昼夜节律调节。综上所述，热水分支提取物具有作为天然抗氧化物质的潜力，而相应的乙醇提取物具有作为调节昼夜节律功能物质的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Korean wood science and technology Materials Science-Materials Science (miscellaneous)

CiteScore

5.20

自引率

0.00%

发文量

期刊介绍： The Journal of the Korean Wood Science and Technology (JKWST) launched in 1973 as an official publication of the Korean Society of Wood Science and Technology has been served as a core of knowledges on wood science and technology. The Journal acts as a medium for the exchange of research in the area of science and technology related to wood, and publishes results on the biology, chemistry, physics and technology of wood and wood-based products. Research results about applied sciences of wood-based materials are also welcome. The Journal is published bimonthly, and printing six issues per year. Supplemental or special issues are published occasionally. The abbreviated and official title of the journal is ''J. Korean Wood Sci. Technol.''. All submitted manuscripts written in Korean or English are peer-reviewed by more than two reviewers. The title, abstract, acknowledgement, references, and captions of figures and tables should be provided in English for all submitted manuscripts.